NUDT11 Antibodies

AND NUDT11 ELISA kits, NUDT11 Proteins

Many biological assays use antibodies to detect NUDT11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NUDT11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NUDT11 antibodies...

We validate the specificity of these antibodies to NUDT11 by testing them on tissues known to express NUDT11 positively and negatively. Browse below to find the NUDT11 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NUDT11 Infographic by Boster Bio

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NUDT11 (NM_018159) Human Over-expression Lysate

Human

$628
Cat # LS055190
100 µg

NUDT11 Overview

Facts about Diphosphoinositol polyphosphate phosphohydrolase 3-beta.

NUDT11 3D structure. Source: alphafold

Diphosphoinositol polyphosphate phosphohydrolase 3-beta (NUDT11)

Cleaves a beta-phosphate in the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it might play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates.

The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate.

Gene Information

Human
Gene Name:	NUDT11
Uniprot:	Q96G61
Entrez:	55190

Family

Belongs to:

Nudix hydrolase family

Alternative Names

APS1DIPP3B; ASP1; Diadenosine 5'-5'''-P1; diphosphoinositol polyphosphate phosphohydrolase 3, beta; diphosphoinositol polyphosphate phosphohydrolase 3-beta; DIPP3b; DIPP3beta; DIPP-3-beta; DIPP3-beta; EC 3.6.1.-; EC 3.6.1.52; FLJ10628; hDIPP3betahAps1; Nucleoside diphosphate-linked moiety X motif 11; nudix (nucleoside diphosphate linked moiety X)-type motif 11; Nudix motif 11; P6-hexaphosphate hydrolase 3-beta

Molecular Weight

Mass (kDA):
18.559 kDA

Genomic Context


Human

Location:	Xp11.22
Sequence:	X; NC_000023.11 (51490011..51496592, complement)

Tissue Specificity

Mainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is also expressed in pancreas and weakly expressed in thymus, prostate, ovary, lung, small intestine and heart.

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Malignant Neoplasms
Neoplasms

Pathways

Dna Repair
Pathogenesis

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NUDT11

References

PMID: 12105228 by Hidaka K., et al. An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.

PMID: 12121577 by Leslie N.R., et al. Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.