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NEDD8 ultimate buster 1 Antibodies
AND NUB1 ELISA kits, NEDD8 ultimate buster 1 Proteins
Many biological assays use antibodies to detect NEDD8 ultimate buster 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NEDD8 ultimate buster 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NEDD8 ultimate buster 1 antibodies...
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NUB1 Infographic by Boster Bio
All NUB1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1412
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1412
1 kit, containing one 96-well plate and all necessary reagents
Human, Monkey, Mouse
ELISA, IHC, WB
$380
Cat # A06089
100ul
Cat # A06089
100ul
Dog, Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M06089
100 µl
Cat # M06089
100 µl
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A06089-2
100 µg/vial
Cat # A06089-2
100 µg/vial
NUB1 Overview
Facts about NEDD8 ultimate buster 1.
NEDD8 ultimate buster 1 (NUB1)
Particular down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates into the proteasome for degradation.
Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. .
Gene Information
| Human | |
|---|---|
| Gene Name: | NUB1 |
| Uniprot: | Q9Y5A7 |
| Entrez: | 51667 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BS4; NEDD8 ultimate buster-1; negative regulator of ubiquitin-like proteins 1NUB1L; NUB1; NUB1L; NY-REN-18 antigen; NY-REN-18; NYREN18NEDD8 ultimate buster 1; Renal carcinoma antigen NY-REN-18
Molecular Weight
Mass (kDA):
70.538 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q36.1 |
| Sequence: | 7; NC_000007.14 (151341699..151378461) |
Tissue Specificity
Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.
Subcellular Localizations
Nucleus. Predominantly nuclear.
Diseases
- Amaurosis
- Leber Congenital Amaurosis
- Blind Vision
- Optic Atrophy, Hereditary, Leber
- Neurodegenerative Disorders
- Parkinson Disease
- Malignant Neoplasms
- Retinal Degeneration
- Dementia
- Lewy Body Disease
- Lymphoma
- Acute Interstitial Pneumonia
Interacting Proteins
- AIPL1
- SF3B4
- TERF1
Pathways
- Conjugation
- Localization
- Cell Cycle
- Cell Growth
- Pathogenesis
- Proteolysis
- Autophagy
- Transport
- Hyperphosphorylation
- Regulation Of Cell Cycle
- Cell Proliferation
PTMs
- Ubiquitination
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NUB1
bosterbio.com/bosterbio-gene-info-cards/NUB1
References
PMID: 11259415 by Kito K., et al. NUB1, a NEDD8-interacting protein, is induced by interferon and down- regulates the NEDD8 expression.
PMID: 12816948 by Tanaka T., et al. Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L.