NT5M Antibodies

AND NT5M ELISA kits, NT5M Proteins

Many biological assays use antibodies to detect NT5M, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NT5M in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NT5M antibodies...

We validate the specificity of these antibodies to NT5M by testing them on tissues known to express NT5M positively and negatively. Browse below to find the NT5M antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NT5M Infographic by Boster Bio

All NT5M Products

Product

Figures

Specificity

Applications

Price

NT5M (NM_020201) Human Recombinant Protein

$1249
Cat # PROTQ9NPB1
20 µg

NT5M (NM_020201) Human Over-expression Lysate

Human

$628
Cat # LS056953
100 µg

Anti-NT5M Antibody Picoband™

Human, Mouse, Rat

ELISA, WB

$370
Cat # A12979-1
100 µg/vial

NT5M Overview

Facts about 5'(3')-deoxyribonucleotidase, mitochondrial.

NT5M 3D structure. Source: alphafold

5'(3')-deoxyribonucleotidase, mitochondrial (NT5M)

Dephosphorylates especially the 5' and 2'(3')- phosphates of uracil and thymine deoxyribonucleotides, and thus protects mitochondrial DNA replication from surplus dTTP. Has only marginal activity towards dIMP and dGMP.

Gene Information

Human
Gene Name:	NT5M
Uniprot:	Q9NPB1
Entrez:	56953

Family

Belongs to:

5'(3')-deoxyribonucleotidase family

Alternative Names

3'-nucleotidase, mitochondrialDNT2; 5' nucleotidase, mitochondrial; 5'; 5(3)-deoxyribonucleotidase; Deoxy-5'-nucleotidase 2; dNT2; dNT-25'(3')-deoxyribonucleotidase, mitochondrial; EC 3.1.3; EC 3.1.3.-; mdN; mitochondrial 5' nucleotidase

Molecular Weight

Mass (kDA):
25.862 kDA

Genomic Context


Human

Location:	17p11.2
Sequence:	17; NC_000017.11 (17303373..17347663)

Tissue Specificity

Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas.

Subcellular Localizations

Mitochondrion.

Diseases

Hereditary Diseases
Hepatitis, Chronic
Hepatitis
Depressive Disorder
Mitochondrial Diseases
Inflammation
Smith-magenis Syndrome
Hepatitis B

Tissue Adhesions
Hepatitis B, Chronic
Dysmyelopoietic Syndromes

Pathways

Transport
Response To Selenium Ion
Cell Adhesion
Regulation Of Calcium Ion-dependent Exocytosis
Transmembrane Transport
Immune Response
Cell Growth
Exocytosis

Localization
Calcium Ion-dependent Exocytosis

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NT5M

References

PMID: 10899995 by Rampazzo C., et al. A deoxyribonucleotidase in mitochondria: involvement in regulation of dNTP pools and possible link to genetic disease.

PMID: 12352955 by Rinaldo-Matthis A., et al. Crystal structure of a human mitochondrial deoxyribonucleotidase.