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- Table of Contents
Facts about Steroidogenic factor 1.
Binds to the Ad4 site located in the promoter region of steroidogenic P450 genes like CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes.
Human | |
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Gene Name: | NR5A1 |
Uniprot: | Q13285 |
Entrez: | 2516 |
Belongs to: |
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nuclear hormone receptor family |
AD4BP; AD4BPSTF-1; Adrenal 4-binding protein; ELP; FTZ1adrenal 4 binding protein; FTZF1; FTZF1nuclear receptor AdBP4; Fushi tarazu factor homolog 1; NR5A1; Nuclear receptor subfamily 5 group A member 1; nuclear receptor subfamily 5, group A, member 1; SF1; SF-1; SF-1POF7; SF1steroidogenic factor 1; Steroid hormone receptor Ad4BP; steroidogenic factor-1
Mass (kDA):
51.636 kDA
Human | |
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Location: | 9q33.3 |
Sequence: | 9; NC_000009.12 (124481236..124507399, complement) |
High expressed in the adrenal cortex, the ovary, the testis, and the spleen (PubMed:9177385).
Nucleus.
PMID: 8806624 by Oba K., et al. Structural characterization of human Ad4bp (SF-1) gene.
PMID: 8938589 by Wong M., et al. Cloning and sequence analysis of the human gene encoding steroidogenic factor 1.