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- Table of Contents
Facts about Nuclear receptor subfamily 2 group C member 2.
Together with NR2C1, forms the center of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half website direct repeat consensus sequences.
Human | |
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Gene Name: | NR2C2 |
Uniprot: | P49116 |
Entrez: | 7182 |
Belongs to: |
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nuclear hormone receptor family |
hTAK1; NR2C2; Nuclear hormone receptor TR4; nuclear receptor subfamily 2 group C member 2; nuclear receptor subfamily 2, group C, member 2; Orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; TAK1; TAK1TR4TR2R1; Testicular receptor 4; TR4 nuclear hormone receptor; TR4
Mass (kDA):
65.414 kDA
Human | |
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Location: | 3p25.1 |
Sequence: | 3; NC_000003.12 (14947583..15049273) |
Nucleus.
PMID: 7708055 by Hirose T., et al. TAK1: molecular cloning and characterization of a new member of the nuclear receptor superfamily.
PMID: 8016112 by Chang C., et al. Human and rat TR4 orphan receptors specify a subclass of the steroid receptor superfamily.