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NPR3 Antibodies
AND NPR3 ELISA kits, NPR3 Proteins
Many biological assays use antibodies to detect NPR3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NPR3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NPR3 antibodies...
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NPR3 Infographic by Boster Bio
All NPR3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # M03589
100 μl
Cat # M03589
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M03589-2
100 µl
Cat # M03589-2
100 µl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M03589-3
100 µl
Cat # M03589-3
100 µl
NPR3 Overview
Facts about Atrial natriuretic peptide receptor 3.
Atrial natriuretic peptide receptor 3 (NPR3)
Receptor for the natriuretic peptide hormones, binding with comparable affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May serve as a clearance receptor for NPPA, NPPB and NPPC, regulating their regional concentrations and effects.
May modulate diuresis, blood pressure and skeletal growth. Does not have guanylate cyclase activity.
Gene Information
| Human | |
|---|---|
| Gene Name: | NPR3 |
| Uniprot: | P17342 |
| Entrez: | 4883 |
Family
| Belongs to: |
|---|
| ANF receptor family |
Alternative Names
ANP-C; ANPR-C; ANPRCFLJ14054; Atrial natriuretic peptide clearance receptor; atrial natriuretic peptide receptor 3; Atrial natriuretic peptide receptor type C; C5orf23; chromosome 5 open reading frame 23; GUCY2B; lgj; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptidereceptor C); NPR3; NPRC; NPR-C; stri
Molecular Weight
Mass (kDA):
59.808 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5p13.3 |
| Sequence: | 5; NC_000005.10 (32689076..32791724) |
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Hypertensive Disease
- Neoplasms
- Dwarfism
- Medulloblastoma
- Diabetes Mellitus
- Hypertrophy
- Cardiovascular Diseases
- Cerebrovascular Accident
- Ischemic Stroke
- Obesity
- Sclerosis
- Learning Disorders
- Primary Lateral Sclerosis
Pathways
- Systemic Acquired Resistance
- Cell Cycle
- Endochondral Bone Growth
- Cell Proliferation
- Localization
- Disease Resistance
- Excretion
- Autophagy
- Cell Adhesion
- Muscle Cell Proliferation
- Programmed Cell Death
- Ossification
- Regulation Of Autophagy
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NPR3
bosterbio.com/bosterbio-gene-info-cards/NPR3
References
PMID: 2162522 by Lowe D.G., et al. cDNA sequence of the human atrial natriuretic peptide clearance receptor.
PMID: 2169733 by Porter J.G., et al. Isolation and functional expression of the human atrial natriuretic peptide clearance receptor cDNA.