NPR2 Antibodies

AND NPR2 ELISA kits, NPR2 Proteins

Many biological assays use antibodies to detect NPR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NPR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NPR2 antibodies...

We validate the specificity of these antibodies to NPR2 by testing them on tissues known to express NPR2 positively and negatively. Browse below to find the NPR2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NPR2 Infographic by Boster Bio

All NPR2 Products

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Product

Figures

Specificity

Applications

Price

Anti-ANPRB NPR2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A02251
100ul

Anti-ANPRB Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M02251
100 μl/vial

Natriuretic Peptide Receptor B (NPR2) (NM_003995) Human Over-expression Lysate

Human

$960
Cat # LS004882
100 µg

NPR2 Overview

Facts about Atrial natriuretic peptide receptor 2.

NPR2 3D structure. Source: alphafold

Atrial natriuretic peptide receptor 2 (NPR2)

Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand.

May play a role in the regulation of skeletal growth. .

Gene Information

Human
Gene Name:	NPR2
Uniprot:	P20594
Entrez:	4882

Family

Belongs to:

adenylyl cyclase class-4/guanylyl cyclase family

Alternative Names

AMDM; ANPb; ANPRB; ECDM; GC-B; GUC2B; NPR2; NPRB; NPRBi; SNSK

Molecular Weight

Mass (kDA):
117.022 kDA

Genomic Context


Human

Location:	9p13.3
Sequence:	9; NC_000009.12 (35782086..35809731)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Dwarfism
Dysplasia
Acromesomelic Dysplasia Syndrome
Neoplasms
Pituitary Diseases
Hypertrophy
Skeletal Dysplasia
Bone Diseases, Developmental
Infertility
Malignant Neoplasms
Heart Failure
Achondroplasia

Malignant Neoplasm Of Lung
Lung Neoplasms
Female Infertility
Hypertensive Disease
Sclerosis
Adenoma
Neoplasm Metastasis

Pathways

Meiosis
Transport
Ossification
Cell Cycle
Prophase
Localization
Cell Cycle Checkpoint
Chondrocyte Proliferation
Endochondral Ossification
Dna Repair
Ovulation
Cell Growth
Autophagy

Secretion
Protein Phosphorylation
Fertilization
Hypersensitivity
Regulation Of Autophagy
Chromosome Segregation
Cartilage Development

PTMs

Phosphorylation

Dephosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NPR2

References

PMID: 2570358 by Chang M.S., et al. Differential activation by atrial and brain natriuretic peptides of two different receptor guanylate cyclases.

PMID: 10082481 by Rehemudula D., et al. Structure of the type B human natriuretic peptide receptor gene and association of a novel microsatellite polymorphism with essential hypertension.