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NPR1 Antibodies
AND NPR1 ELISA kits, NPR1 Proteins
Many biological assays use antibodies to detect NPR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NPR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NPR1 antibodies...
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NPR1 Infographic by Boster Bio
All NPR1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, IF, ICC, WB
$370
Cat # A01042
100 μg/vial
Cat # A01042
100 μg/vial
Human, Mouse, Rat
WB
$523
Cat # M01042
100 µl
Cat # M01042
100 µl
NPR1 Overview
Facts about Atrial natriuretic peptide receptor 1.
Atrial natriuretic peptide receptor 1 (NPR1)
Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | NPR1 |
| Uniprot: | P16066 |
| Entrez: | 4881 |
Family
| Belongs to: |
|---|
| adenylyl cyclase class-4/guanylyl cyclase family |
Alternative Names
ANPa; ANP-A; ANPRA; ANPR-A; ANPRAEC 4.6.1.2; atrial natriuretic peptide receptor 1; Atrial natriuretic peptide receptor type A; atrionatriuretic peptide receptor A; GC-A; Guanylate cyclase A; GUC2A; GUCY2A; natriuretic peptide A type receptor; natriuretic peptide receptor A; natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptidereceptor A); NPR1; NPRA; NPR-A; Pndr
Molecular Weight
Mass (kDA):
118.919 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q21.3 |
| Sequence: | 1; NC_000001.11 (153678649..153693992) |
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Plant Diseases
- Hypertrophy
- Hypertensive Disease
- Cardiac Hypertrophy
- Fibrosis
- Infective Disorder
- Infectious Bovine Keratoconjunctivitis
- Physiological Stress
- Heart Failure
- Dwarfism
- Cell Invasion
- Bacterial Infections
Pathways
- Systemic Acquired Resistance
- Disease Resistance
- Cell Death
- Defense Response
- Localization
- Pathogenesis
- Immune Response
- Induced Systemic Resistance
- Transport
- Gene Silencing
- Programmed Cell Death
- Virulence
- Senescence
PTMs
- Phosphorylation
- Dephosphorylation
- Ubiquitination
- Nitrosylation
- Methylation
Research Areas
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NPR1
bosterbio.com/bosterbio-gene-info-cards/NPR1
References
PMID: 2569967 by Lowe D.G., et al. Human atrial natriuretic peptide receptor defines a new paradigm for second messenger signal transduction.
PMID: 9618281 by Takahashi Y., et al. Organization of the human natriuretic peptide receptor A gene.