This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
5 Citations 3 Q&As
16 Citations 5 Q&As
8 Citations 4 Q&As
2 Citations
Facts about Nitric oxide synthase, brain.
Probably has nitrosylase action and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR. .
Human | |
---|---|
Gene Name: | NOS1 |
Uniprot: | P29475 |
Entrez: | 4842 |
Belongs to: |
---|
NOS family |
bNOS; brain; Constitutive NOS; EC 1.14.13.39; IHPS1; Neuronal NOS; nitric oxide synthase 1 (neuronal); nNOS; N-NOS; nNOSNOS type I; NOS; NOS1; Peptidyl-cysteine S-nitrosylase NOS1
Mass (kDA):
160.97 kDA
Human | |
---|---|
Location: | 12q24.22 |
Sequence: | 12; NC_000012.12 (117208142..117361802, complement) |
Isoform 1 is ubiquitously expressed: detected in skeletal muscle and brain, also in testis, lung and kidney, and at low levels in heart, adrenal gland and retina. Not detected in the platelets. Isoform 3 is expressed only in testis. Isoform 4 is detected in testis, skeletal muscle, lung, and kidney, at low levels in the brain, but not in the heart and adrenal gland.
Cell membrane, sarcolemma; Peripheral membrane protein. Cell projection, dendritic spine. In skeletal muscle, it is localized beneath the sarcolemma of fast-twitch muscle fiber by associating with the dystrophin glycoprotein complex. In neurons, enriched in dendritic spines (By similarity).
PMID: 7528745 by Hall A.V., et al. Structural organization of the human neuronal nitric oxide synthase gene (NOS1).
PMID: 7515942 by Fujisawa H., et al. Expression of two types of nitric oxide synthase mRNA in human neuroblastoma cell lines.
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page