Neuromedin-U receptor 1 Antibodies

Neuromedin-U receptor 1 (NMUR1)

Receptor for the neuromedin-U and neuromedin-S neuropeptides. .

Gene Information

Human
Gene Name:	NMUR1
Uniprot:	Q9HB89
Entrez:	10316

Family

Belongs to:
G-protein coupled receptor 1 family

Alternative Names

(FM-3); FM3; FM-3; G protein-coupled receptor 66; GPC-R; GPR66; GPR66G-protein coupled receptor 66; G-protein coupled receptor FM-3; Neuromedin U R1; neuromedin U receptor 1; Neuromedin UR1; neuromedin-U receptor 1; NMU1R; NMUR1; NMU-R1

Molecular Weight

Mass (kDA):
47.351 kDA

Genomic Context

Human
Location:	2q37.1
Sequence:	2; NC_000002.12 (231519903..231530456, complement)

Tissue Specificity

Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

• Neonatal Maladjustment Syndrome
• Nervousness
• Obesity
• Pertussis
• Pituitary Diseases
• Pain
• Diabetes Mellitus
• Inflammation
• Disease Of Adrenal Medulla
• Eating Disorders
• Malignant Neoplasm Of Kidney
• Tumor Progression

• Von Hippel-lindau Syndrome
• Hypoxia
• Kidney Neoplasm
• Acth Hypersecretion
• Carcinoma
• Malignant Neoplasms
• Neoplasms

Pathways

• Energy Homeostasis
• Secretion
• Regulation Of Energy Homeostasis
• Cell Proliferation
• Insulin Secretion
• Metaphase
• Glucose Homeostasis
• Circadian Rhythm
• Somatostatin Secretion
• Immune Response
• Synaptic Transmission
• Regulation Of Gonadotropin Secretion
• Conjugation

• Spermatogenesis
• Reflex
• Regeneration
• Gonadotropin Secretion
• Regulation Of Insulin Secretion
• Sensory Perception
• Corticosterone Secretion

PTMs

• Phosphorylation

Research Areas

• GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NMUR1

Best Uses Of The NMUR1 Marker

Boster Bio stocks antibodies against NMUR1 They are highly specific, affinity, and validated by multiple platforms. Boster offers product credits for the first reviewers to their products. This program encourages scientists to review their products and to contribute to the discussion. They want you to enjoy these products. However, not every antibody is right for you. Boster has an antibody that will work in your research, whether it is in animal models or cells.

Boster Bio: Anti-Mineralocorticoid Receptor/NR3C2 antibody

The nuclear hormone-receptor family includes the human mineralsocorticoid receptor/NR3C2. It is a periphery membrane protein that is nuclear in the absence it ligand. It is expressed primarily in the kidney, sweat glands, and cardiomyocytes but at lower levels in the epidermis and colon enterocytes. It is a member of the NR3 subfamily and belongs to the nuclear hormone receptors family.

The NR3C2 protein encodes the mineralocorticoid receptor (MR). This protein functions as a liganddependent transcription factor. It binds to NR3C2 to regulate gene transcript. It has been implicated also in autosomal dysfunction and tumor suppression. There are many clinical applications and molecular characteristics.

Boster Bio Transfection Reagent

Boster Bio manufactures this antibody and it reacts with NMUR1 gene. This protein is found in human cells. It is stable at -20degC and can be stored at 4degC for up to one month. The NMUR1 antibody is a liquid and can be purchased at various prices. Costs for blocking peptides vary depending on the length and complexity of the immunogen.