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- Table of Contents
Facts about NACHT, LRR and PYD domains-containing protein 7.
Inhibits CASP1/caspase-1-Reliant IL1B secretion.
.Human | |
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Gene Name: | NLRP7 |
Uniprot: | Q8WX94 |
Entrez: | 199713 |
Belongs to: |
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NLRP family |
NACHT, LRR and PYD domains-containing protein 7
Mass (kDA):
111.807 kDA
Human | |
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Location: | 19q13.42 |
Sequence: | 19; NC_000019.10 (54923509..54965184, complement) |
Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle.
PMID: 12019269 by Wang L., et al. PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing.
PMID: 12563287 by Tschopp J., et al. NALPs: a novel protein family involved in inflammation.