NLRC4 Antibodies

AND NLRC4 ELISA kits, NLRC4 Proteins

Many biological assays use antibodies to detect NLRC4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NLRC4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NLRC4 antibodies...

We validate the specificity of these antibodies to NLRC4 by testing them on tissues known to express NLRC4 positively and negatively. Browse below to find the NLRC4 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NLRC4 Infographic by Boster Bio

All NLRC4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CARD12/NLRC4 Antibody Picoband®

5 Q&As

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # PB9673
100 μg/vial

Anti-Ipaf NLRC4 Antibody

Human

ELISA, IF, ICC, WB

$449
Cat # A00525
0.1 mg

Anti-NLRC4 Antibody

Rat

ELISA, IF, IHC, ICC

$405
Cat # A00525-1
100ul

CARD12 (NLRC4) (NM_021209) Human Over-expression Lysate

Human

$628
Cat # LS058484
100 µg

NLRC4 Overview

Facts about NLR family CARD domain-containing protein 4.

NLRC4 3D structure. Source: alphafold

NLR family CARD domain-containing protein 4 (NLRC4)

Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and reacts by building an inflammasome complex that boosts caspase-1 activation, cytokine production and macrophage pyroptosis (PubMed:15107016). The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria (By similarity).

Gene Information

Human
Gene Name:	NLRC4
Uniprot:	Q9NPP4
Entrez:	58484

Family

Belongs to:

No superfamily

Alternative Names

CARD12leucine rich repeat and CARD domaincontaining 4; caspase recruitment domain family, member 12; Caspase recruitment domain-containing protein 12; Clan protein; CLAN1ipaf; CLANCARD, LRR, and NACHT-containing protein; CLR2.1; Ice protease-activating factor; Ipaf; NLR family, CARD domain containing 4

Molecular Weight

Mass (kDA):
116.159 kDA

Genomic Context


Human

Location:	2p22.3
Sequence:	2; NC_000002.12 (32224449..32265743, complement)

Tissue Specificity

Isoform 2 is expressed ubiquitously, although highly expressed in lung and spleen. Isoform 1 is highly expressed in lung, followed by leukocytes especially monocytes, lymph node, colon, brain, prostate, placenta, spleen, bone marrow and fetal liver. Isoform 4 is only detected in brain.