Neuroligin-1 (NLGN1)

Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and likely mediates its effects by recruiting and clustering other synaptic proteins.

May promote the initial formation of synapses, but is not vital for this. In vitro, triggers the de novo formation of presynaptic structures.