NIPA1 Antibodies

AND NIPA1 ELISA kits, NIPA1 Proteins

Many biological assays use antibodies to detect NIPA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NIPA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NIPA1 antibodies...

We validate the specificity of these antibodies to NIPA1 by testing them on tissues known to express NIPA1 positively and negatively. Browse below to find the NIPA1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NIPA1 Infographic by Boster Bio

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Anti-Magnesium transporter NIPA1 NIPA1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A06024
100ul

NIPA1 Overview

Facts about Magnesium transporter NIPA1.

NIPA1 3D structure. Source: alphafold

Magnesium transporter NIPA1 (NIPA1)

Acts as a Mg(2+) transporter.
Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity).

. .

Gene Information

Human
Gene Name:	NIPA1
Uniprot:	Q7RTP0
Entrez:	123606

Family

Belongs to:

NIPA family

Alternative Names

magnesium transporter NIPA1; MGC102724; non imprinted in Prader-Willi/Angelman syndrome 1; SPG6

Molecular Weight

Mass (kDA):
34.562 kDA

Genomic Context


Human

Location:	15q11.2
Sequence:	15; NC_000015.10 (22786225..22829789)

Tissue Specificity

Widely expressed with highest levels in neuronal tissues.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Early endosome. Recruited to the cell membrane in response to low extracellular magnesium.

Diseases

Spastic Paraplegia, Hereditary
Paraplegia
Spastic Paraplegia
Neurodegenerative Disorders
Weakness
Muscle Spasticity
Peroneal Muscular Atrophy With Pyramidal Features, Autosomal Dominant
Prader-willi Syndrome
Angelman Syndrome
Sclerosis
Paraparesis
Paraparesis, Spastic

Nervousness
Cytogenetic Abnormality
Primary Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Atrophy
Impaired Cognition
Gait Abnormality

Pathways

Pathogenesis
Methylation
Transport
Localization
Transposition
System Development
Cell Death
Nervous System Development
Endocytosis

Rna Processing
Central Nervous System Development
Axonogenesis

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NIPA1

References

PMID: 14508708 by Chai J.-H., et al. Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons.

PMID: 12805275 by Toyoda N., et al. Analysis of mRNA with microsomal fractionation using a SAGE-based DNA microarray system facilitates identification of the genes encoding secretory proteins.