This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Ninein.
May play a role in microtubule nucleation, by recruiting the gamma-tubulin ring complex to the centrosome (PubMed:15784680). Overexpression doesn't perturb nucleation or elongation of microtubules but suppresses release of microtubules (By similarity).
Mouse | |
---|---|
Gene Name: | Nin |
Uniprot: | Q61043 |
Entrez: | 18080 |
Belongs to: |
---|
No superfamily |
Glycogen synthase kinase 3 beta-interacting protein; GSK3B-interacting protein; hNinein; KIAA1565; ninein (GSK3B interacting protein); ninein centrosomal protein; ninein
Mass (kDA):
243.718 kDA
Mouse | |
---|---|
Location: | 12|12 C2 |
Sequence: | 12; |
Widely expressed. Highly expressed in spleen, bone marrow and skin. Weakly expressed in liver and small intestine. Expressed in brain.
PMID: 8834802 by Bouckson-Castaing V., et al. Molecular characterisation of ninein, a new coiled-coil protein of the centrosome.
PMID: 15784680 by Delgehyr N., et al. Microtubule nucleation and anchoring at the centrosome are independent processes linked by ninein function.