Neogenin Antibodies

AND NEO1 ELISA kits, Neogenin Proteins

Many biological assays use antibodies to detect Neogenin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Neogenin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Neogenin antibodies...

We validate the specificity of these antibodies to Neogenin by testing them on tissues known to express NEO1 positively and negatively. Browse below to find the NEO1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NEO1 Infographic by Boster Bio

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Neogenin (NEO1) (NM_002499) Human Over-expression Lysate

Human

$960
Cat # LS004756
100 µg

NEO1 Overview

Facts about Neogenin.

NEO1 3D structure. Source: alphafold

Neogenin (NEO1)

Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families.

Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive reaction. .

Gene Information

Human
Gene Name:	NEO1
Uniprot:	Q92859
Entrez:	4756

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

HsT17534; IGDCC2DKFZp547B146; Immunoglobulin superfamily DCC subclass member 2; NEO; NEO1; neogenin (chicken) homolog 1; neogenin 1; neogenin homolog 1; Neogenin; NGN; NGNDKFZp547A066

Molecular Weight

Mass (kDA):
160.017 kDA

Genomic Context


Human

Location:	15q24.1
Sequence:	15; NC_000015.10 (73051715..73305206)

Tissue Specificity

Widely expressed and also in cancer cell lines.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Nervousness
Malignant Neoplasms
Neoplasms
Colorectal Cancer
Inflammation
Tissue Adhesions
Malignant Tumor Of Colon
Inflammatory Response
Peritonitis
Disease Of Adrenal Medulla
Adenoma
Glioma
Neoplasm Invasiveness

Infertility
Carcinoma
Tumor Angiogenesis
Medulloblastoma
Bacterial Infections
Meningioma
Persistent Fetal Circulation Syndrome

Interacting Proteins

Pathways

Axon Guidance
Transport
Cell Migration
Endocytosis
Localization
Leukocyte Migration
Inflammatory Response
Protein Transport
Cell Adhesion
Acute Inflammatory Response
Developmental Process
Photosynthesis
Immune Response

Muscle Contraction
Inner Ear Development
M Phase
Membrane Budding
Sporulation
Ribosome Assembly
Membrane Biogenesis

PTMs

Phosphorylation
Glycosylation

Methylation
Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NEO1

References

PMID: 9121761 by Meyerhardt J.A., et al. Identification and characterization of neogenin, a DCC-related gene.

PMID: 9169140 by Vielmetter J., et al. Molecular characterization of human neogenin, a DCC-related protein, and the mapping of its gene (NEO1) to chromosomal position 15q22.3- q23.