NELL2 Antibodies

AND NELL2 ELISA kits, NELL2 Proteins

Many biological assays use antibodies to detect NELL2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NELL2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NELL2 antibodies...

We validate the specificity of these antibodies to NELL2 by testing them on tissues known to express NELL2 positively and negatively. Browse below to find the NELL2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NELL2 Infographic by Boster Bio

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NELL2 (NM_001145110) Human Recombinant Protein

$813
Cat # PROTQ99435
20 µg

NELL2 Overview

Facts about Protein kinase C-binding protein NELL2.

NELL2 3D structure. Source: alphafold

Protein kinase C-binding protein NELL2 (NELL2)

Required for neuron survival through the modulation of MAPK pathways (By similarity). Involved in the regulation of hypothalamic GNRH secretion and the control of puberty (By similarity).

Gene Information

Human
Gene Name:	NELL2
Uniprot:	Q99435
Entrez:	4753

Family

Belongs to:

No superfamily

Alternative Names

Mel91; nel (chicken)-like 2; NELL2; NEL-like 2 (chicken); NEL-like protein 2; Nel-related protein 2; NRP2; NRP2neural epidermal growth factor-like 2; protein kinase C-binding protein NELL2

Molecular Weight

Mass (kDA):
91.346 kDA

Genomic Context


Human

Location:	12q12
Sequence:	12; NC_000012.12 (44508275..44921848, complement)

Subcellular Localizations

Secreted.

Diseases

Malignant Neoplasms
Nervousness
Neoplasms
Carcinoma
Crest Syndrome
Disease Of Adrenal Medulla
Kidney Neoplasm
Benign Prostatic Hypertrophy
Renal Cell Carcinoma
Adenocarcinoma
Prostatic Hyperplasia
Malignant Neoplasm Of Kidney
Cell Transformation, Neoplastic

Brain Neoplasms
Neoplasms, Neuroepithelial
Burkitt Lymphoma
Malignant Tumor Of Colon
Malignant Neoplasm Of Urinary Bladder
Dysplasia
Tumor Angiogenesis

Interacting Proteins

GFI1B
ROBO3

Pathways

Brain Development
Neurogenesis
Localization
Cell Death
Cell Growth
Secretion
Transport
Neural Plate Formation
Cell Migration
Cell Proliferation
Cell Development
Synaptic Transmission

Neuron Differentiation
Chondrocyte Hypertrophy
Axon Guidance
Angiogenesis
Pathogenesis
Rna Interference
Oncogenesis

PTMs

Phosphorylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NELL2

References

PMID: 8975702 by Watanabe T.K., et al. Cloning and characterization of two novel human cDNAs (NELL1 and NELL2) encoding proteins with six EGF-like repeats.