NELL1 Antibodies

AND NELL1 ELISA kits, NELL1 Proteins

Many biological assays use antibodies to detect NELL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NELL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NELL1 antibodies...

We validate the specificity of these antibodies to NELL1 by testing them on tissues known to express NELL1 positively and negatively. Browse below to find the NELL1 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NELL1 Infographic by Boster Bio

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NELL1 Overview

Facts about Protein kinase C-binding protein NELL1.

NELL1 3D structure. Source: alphafold

Protein kinase C-binding protein NELL1 (NELL1)

Plays a role in the control of cell growth and differentiation. Promotes osteoblast cell differentiation and terminal mineralization.

Gene Information

Human
Gene Name:	NELL1
Uniprot:	Q92832
Entrez:	4745

Family

Belongs to:

No superfamily

Alternative Names

FLJ45906; IDH3GL; nel (chicken)-like 1; NELL1; NEL-like 1 (chicken); NEL-like protein 1; Nel-related protein 1; neural epidermal growth factor-like 1; NRP1; protein kinase C-binding protein NELL1

Molecular Weight

Mass (kDA):
89.635 kDA

Genomic Context


Human

Location:	11p15.1
Sequence:	11; NC_000011.10 (20669551..21575686)

Subcellular Localizations

Cytoplasm. Nucleus envelope. Secreted. Colocalizes with ATRAID on the nuclear envelope and the perinuclear region.

Diseases

Craniosynostosis
Congenital Abnormality
Malignant Neoplasms
Neoplasms
Dysplasia
Congenital Abnormal Synostosis
Crohn Disease
Inflammatory Bowel Diseases
Cleidocranial Dysplasia
Carcinoma
Ulcer
Lymphoma
Osteoporosis

Adenocarcinoma
Hypertrophy
Craniofacial Abnormalities
Nervousness
Colitis
Tissue Adhesions
Ulcerative Colitis

Interacting Proteins

ATRAID

Pathways

Regeneration
Osteoblast Differentiation
Cell Differentiation
Methylation
Ossification
Chondrocyte Proliferation
Endochondral Ossification
Localization
Cell Growth
Pathogenesis
Transport
Cellular Response To Dsrna
Cell Adhesion

Cell Migration
Gene Silencing
Dna Demethylation
Osteoblast Proliferation
Chondrocyte Hypertrophy
Translation
Axon Guidance

PTMs

Phosphorylation

Methylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NELL1

References

PMID: 8975702 by Watanabe T.K., et al. Cloning and characterization of two novel human cDNAs (NELL1 and NELL2) encoding proteins with six EGF-like repeats.

PMID: 21723284 by Zou X., et al. NELL-1 binds to APR3 affecting human osteoblast proliferation and differentiation.