NEK1 Antibodies

AND NEK1 ELISA kits, NEK1 Proteins

Many biological assays use antibodies to detect NEK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NEK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NEK1 antibodies...

We validate the specificity of these antibodies to NEK1 by testing them on tissues known to express NEK1 positively and negatively. Browse below to find the NEK1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NEK1 Infographic by Boster Bio

All NEK1 Products

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Anti-NEK1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A04380
100ul

NEK1 Overview

Facts about Serine/threonine-protein kinase Nek1.

NEK1 3D structure. Source: alphafold

Serine/threonine-protein kinase Nek1 (NEK1)

Phosphorylates serines and threonines, but also appears to have tyrosine kinase activity (PubMed:20230784). Involved in DNA damage checkpoint control and for proper DNA damage repair (PubMed:20230784).

In response to injury that includes DNA damage, NEK1 phosphorylates VDAC1 to limit mitochondrial cell death (PubMed:20230784). May be implicated in the control of meiosis (By similarity).

Gene Information

Human
Gene Name:	NEK1
Uniprot:	Q96PY6
Entrez:	4750

Family

Belongs to:

protein kinase superfamily

Alternative Names

DKFZp686D06121; DKFZp686K12169; EC 2.7.11; EC 2.7.11.1; KIAA1901MGC138800; Never in mitosis A-related kinase 1; NIMA (never in mitosis gene a)-related kinase 1; NimA-related protein kinase 1; NY-REN-55; protein-serine/threonine kinase; Renal carcinoma antigen NY-REN-55; serine/threonine-protein kinase Nek1; SRPS2

Molecular Weight

Mass (kDA):
142.828 kDA

Genomic Context


Human

Location:	4q33
Sequence:	4; NC_000004.12 (169392809..169612629, complement)

Tissue Specificity

High fetal expression in the brain and kidney.

Subcellular Localizations

Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Associated with the pericentriolar material (PubMed:21211617). Localizes to centrosome during interphase and mitosis (By similarity). Translocated from cytoplasm to discrete nuclear foci at sites of DNA damage (PubMed:15604234).