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- Table of Contents
Facts about Serine/threonine-protein kinase Nek11.
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Human | |
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Gene Name: | NEK11 |
Uniprot: | Q8NG66 |
Entrez: | 79858 |
Belongs to: |
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protein kinase superfamily |
EC 2.7.11; EC 2.7.11.1; FLJ23495; Never in mitosis A-related kinase 11; NIMA (never in mitosis gene a)- related kinase 11; NimA-related protein kinase 11; serine/threonine-protein kinase Nek11
Mass (kDA):
74.192 kDA
Human | |
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Location: | 3q22.1 |
Sequence: | 3; NC_000003.12 (131026851..131350465) |
Poorly expressed in cerebellum, trachea, lung, appendix, and uterus.
Nucleus. Nucleus, nucleolus. Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase (PubMed:12154088). Accumulates in the nucleolus in G1/S-arrested cells (PubMed:15161910).
PMID: 12154088 by Noguchi K., et al. Nek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responses.
PMID: 15161910 by Noguchi K., et al. Nucleolar Nek11 is a novel target of Nek2A in G1/S-arrested cells.