NEFH Antibodies

AND NEFH ELISA kits, NEFH Proteins

Many biological assays use antibodies to detect NEFH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NEFH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NEFH antibodies...

We validate the specificity of these antibodies to NEFH by testing them on tissues known to express NEFH positively and negatively. Browse below to find the NEFH antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NEFH Infographic by Boster Bio

All NEFH Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-NEFH Antibody (Monoclonal, N52)

12 Citations 5 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # MA1071
100 μg/vial

Anti-NEFH/Nf H Rabbit Monoclonal Antibody

4 Citations 1 Q&As

Human, Mouse, Rat

IHC, WB

$370
Cat # M05307-2
100 μl

Anti-Neurofilament NF-H NEFH Antibody

2 Citations 1 Q&As

Bovine, Equine, Human, Mouse, Pig, Rat

IF, IHC, WB

$299
Cat # M05307-6
100ul

Anti-Phosphorylated Neurofilament NF-H NEFH Antibody

1 Citations

Bovine, Canine, Equine, Human, Mouse, Pig, Rat

IF, IHC, WB

$299
Cat # M05307-7
50ul

Anti-Nefh Antibody Picoband®

17 Citations

Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A05307
100 μg/vial

NFH (NEFH) (NM_021076) Human Over-expression Lysate

Human

$960
Cat # LS004744
100 µg

NEFH Overview

Facts about Neurofilament heavy polypeptide.

NEFH 3D structure. Source: alphafold

Neurofilament heavy polypeptide (NEFH)

Neurofilaments usually contain three intermediate filament proteins: L, L, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that isn't subserved by the two smaller NF proteins.

Gene Information

Human
Gene Name:	NEFH
Uniprot:	P12036
Entrez:	4744

Family

Belongs to:

intermediate filament family

Alternative Names

200 kDa neurofilament protein; KIAA0845; NEFH; Neurofilament Heavy (200kDa); neurofilament heavy polypeptide; Neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide; NF200; NFH; NF-H

Molecular Weight

Mass (kDA):
112.479 kDA

Genomic Context


Human

Location:	22q12.2
Sequence:	22; NC_000022.11 (29480218..29491390)

Subcellular Localizations

Cytoplasm.

Diseases

Neoplasms
Sclerosis
Primary Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Malignant Neoplasms
Neurofibromatoses
Neurofibromatosis 2
Nervousness
Carcinoma
Neurilemmoma
Nerve Degeneration
Acoustic Neuroma
Esophageal Neoplasms

Squamous Cell Carcinoma Of Esophagus
Neurodegenerative Disorders
Motor Neuron Disease
Malignant Squamous Cell Neoplasm
Complete Hearing Loss
Leukemia
Mastitis-metritis-agalactia Syndrome

Pathways

Localization
Methylation
Pathogenesis
Cell Proliferation
Gene Silencing
Dna Methylation
Reflex
Cell Cycle
Cellular Localization

Stem Cell Proliferation
Cell Growth
Phototransduction
Glycolysis

PTMs

Phosphorylation

Methylation

Research Areas

Cell Biology
Cellular Markers
Neurodegeneration
Neuronal Cell Markers
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NEFH

References

PMID: 3138108 by Lees J.F., et al. The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it.

PMID: 8621664 by Mukai H., et al. PKN associates and phosphorylates the head-rod domain of neurofilament protein.

30 Publications of Boster NEFH Antibodies & ELISA Kits

PubMed ID: PMID:31966489, Gene silencing NMII promotes axonal regeneration against contusive spinal cord i...
PubMed ID: 10.3727/096368910X528102, Bone Marrow Mesenchymal Stem Cells and Electroacupuncture Downregulate the Inhib...
PubMed ID: 10.3109/09273948.2013.806989, Improved Retinal Ganglion Cell Survival through Retinal Microglia Suppression by...
PubMed ID: 10.26355/eurrev_201712_14018, Apolipoprotein E 4 triggers multiple pathway-mediated Ca2+ overload, causes CaMK...
PubMed ID: 10.12659/MSM.900893, Changes in the Expression of miR-34a and its Target Genes Following Spinal Cord ...
PubMed ID: 10.1186/s12974-016-0546-2, Downregulation of CD47 and CD200 in patients with focal cortical dysplasia type ...
PubMed ID: 10.1093/jnen/nlv003, Increased Expression and Cellular Localization of P2X7R in Cortical Lesions of P...
PubMed ID: 10.1038/sc.2008.112, Vaccination with dendritic cells pulsed with homogenate protein of spinal cord p...
PubMed ID: 10.1021/acsami.1c01904, Biocompatible Chitin Hydrogel Incorporated with PEDOT Nanoparticles for Peripher...
PubMed ID: 10.1016/j.neulet.2015.04.038, Human mesenchymal stem cells improve the neurodegeneration of femoral nerve in a...
PubMed ID: 10.1016/j.neulet.2013.10.024, Amelioration of β-amyloid-induced cognitive dysfunction and hippocampal axon de...
PubMed ID: 10.1016/j.brainres.2010.08.072, Implantation of adult bone marrow-derived mesenchymal stem cells transfected wit...
PubMed ID: 10.1007/s12031-013-0114-5, Endogenous Subventricular Zone Neural Progenitors Contribute to the Formation an...
PubMed ID: 10.1007/s10072-014-2014-z, Altered expression of neurofilament 200 and amyloid-β peptide (1–40) in a rat...
PubMed ID: , Cograft of neural stem cells and schwann cells overexpressing TrkC and neurotrop...
PubMed ID: 33582188, Wu K,Yue J,Shen K,He J,Zhu G,Liu S,Yang H,Zhang C.Expression and cellular distri...
PubMed ID: 33285262, Wu K,Yue J,Shen K,He J,Zhu G,Liu S,Zhang C,Yang H. Increased Expression of Fibro...
PubMed ID: 27780189, Changes in the Expression of miR-34a and its Target Genes Following Spinal Cord ...
PubMed ID: 27765894, MicroRNA-30b regulates expression of the sodium channel Nav17 in nerve injury-in...
PubMed ID: 23979841, Neuron-derived IgG Protects Neurons from Complement-dependent Cytotoxicity
PubMed ID: 23935920, An Acetylcholinesterase Antibody-Based Quartz Crystal Microbalance for the Rapid...

*Showing only the more recent 20. More publications can be found for each product on its corresponding product page