NEDD4L Antibodies

AND NEDD4L ELISA kits, NEDD4L Proteins

Many biological assays use antibodies to detect NEDD4L, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NEDD4L in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NEDD4L antibodies...

We validate the specificity of these antibodies to NEDD4L by testing them on tissues known to express NEDD4L positively and negatively. Browse below to find the NEDD4L antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NEDD4L Infographic by Boster Bio

All NEDD4L Products

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Product

Figures

Specificity

Applications

Price

Anti-NEDD4-2 NEDD4L Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, WB

$370
Cat # M01595
100 μl

Anti-NEDD4-2/NEDD4L Antibody Picoband®

6 Q&As

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, ICC, WB

$370
Cat # A01595-1
100 μg/vial

Anti-NEDD4L (phospho-S448) Antibody

Human, Mouse, Rat

$482
Cat # A01595S448
100ul

NEDD4L Overview

Facts about E3 ubiquitin-protein ligase NEDD4-like.

NEDD4L 3D structure. Source: alphafold

E3 ubiquitin-protein ligase NEDD4-like (NEDD4L)

E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Inhibits TGF-beta signaling by triggering SMAD2 and TGFBR1 ubiquitination and proteasome-dependent degradation.

Promotes ubiquitination and internalization of different plasma membrane channels like ENaC, SCN2A/Nav1.2, SCN3A/Nav1.

Gene Information

Human
Gene Name:	NEDD4L
Uniprot:	Q96PU5
Entrez:	23327

Family

Belongs to:

No superfamily

Alternative Names

E3 ubiquitin-protein ligase NEDD4-like; EC 6.3.2; EC 6.3.2.-; FLJ33870; hNedd4-2; KIAA0439ubiquitin-protein ligase NEDD4-like; NEDD4.2; NEDD4-2; NEDL3; neural precursor cell expressed, developmentally down-regulated 4-like; neural precursor cell expressed, developmentally down-regulated gene 4-like; RSP5ubiquitin-protein ligase Rsp5

Molecular Weight

Mass (kDA):
111.932 kDA

Genomic Context


Human

Location:	18q21.31
Sequence:	18; NC_000018.10 (58044226..58401540)

Tissue Specificity

Ubiquitously expressed, with highest levels in prostate, pancreas and kidney (PubMed:14615060, PubMed:15496141, PubMed:19664597). Expressed in melanocytes (PubMed:23999003).