NDUFA8 Antibodies

AND NDUFA8 ELISA kits, NDUFA8 Proteins

Many biological assays use antibodies to detect NDUFA8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDUFA8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDUFA8 antibodies...

We validate the specificity of these antibodies to NDUFA8 by testing them on tissues known to express NDUFA8 positively and negatively. Browse below to find the NDUFA8 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NDUFA8 Infographic by Boster Bio

All NDUFA8 Products

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Product

Figures

Specificity

Applications

Price

Anti-NDUFA8 Antibody

6 Q&As

Human, Mouse

IHC, WB

$360
Cat # A10547
100 µl

Anti-NDUFA8 (P141) Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A10547-1
100ul

NDUFA8 (NM_014222) Human Over-expression Lysate

Human

$628
Cat # LS004702
100 µg

Anti-NDUFA8 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A10547-2
100 µg/vial

NDUFA8 Overview

Facts about NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8.

NDUFA8 3D structure. Source: alphafold

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (NDUFA8)

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.

The immediate electron acceptor for the enzyme is believed to be ubiquinone. .

Gene Information

Human
Gene Name:	NDUFA8
Uniprot:	P51970
Entrez:	4702

Family

Belongs to:

complex I NDUFA8 subunit family

Alternative Names

CI-19KD; CI-PGIV; complex I PGIV subunit; Complex I-19kD; Complex I-PGIV; MGC793; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8 (19kD, PGIV); NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; NADH:ubiquinone oxidoreductase PGIV subunit; NADH-ubiquinone oxidoreductase 19 kDa subunit; PGIV

Molecular Weight

Mass (kDA):
20.105 kDA

Genomic Context


Human

Location:	9q33.2
Sequence:	9; NC_000009.12 (122132466..122159779, complement)

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space. Mitochondrion.

Diseases

Nicotinamide Adenine Dinucleotide Coenzyme Q Reductase Deficiency
Leigh Disease
Basal Cell Carcinoma
Leukoencephalopathy, Progressive Multifocal
Acidosis
Skin Neoplasms
Mitochondrial Encephalomyopathies
Inborn Errors Of Metabolism
Malignant Neoplasm Of Breast
Ataxia
Malignant Neoplasm Of Skin
Leukoencephalopathies
Malignant Tumor Of Colon

Muscle Hypotonia
Carcinogenesis
Telomere Shortening
Cardiomyopathies
Malignant Neoplasms
Neoplasms
Acidosis, Lactic

Interacting Proteins

NDUFS3

Pathways

Localization
Senescence
Cell Cycle
Cellular Senescence
Aging
Oxidative Phosphorylation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDUFA8

References

PMID: 9860297 by Triepels R., et al. The nuclear-encoded human NADH:ubiquinone oxidoreductase NDUFA8 subunit: cDNA cloning, chromosomal localization, tissue distribution, and mutation detection in complex-I-deficient patients.

PMID: 9150947 by Sarto C., et al. Renal cell carcinoma and normal kidney protein expression.