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- Table of Contents
Facts about NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12.
The immediate electron acceptor for the enzyme is believed to be ubiquinone. .
Human | |
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Gene Name: | NDUFA12 |
Uniprot: | Q9UI09 |
Entrez: | 55967 |
Belongs to: |
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complex I NDUFA12 subunit family |
13 kDa differentiation-associated protein; B17.2,13kDa differentiation-associated protein; CIB17.2; CI-B17.2; complex I B17.2 subunit; Complex I-B17.2; DAP13NADH-ubiquinone oxidoreductase subunit B17.2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; NADH: ubiquinone oxidoreductase
Mass (kDA):
17.114 kDA
Human | |
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Location: | 12q22 |
Sequence: | 12; NC_000012.12 (94971328..95003713, complement) |
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
PMID: 10830904 by Triepels R., et al. Characterization of the human complex I NDUFB7 and 17.2-kDa cDNAs and mutational analysis of 19 genes of the HP fraction in complex I- deficient-patients.
PMID: 21617257 by Ostergaard E., et al. Respiratory chain complex I deficiency due to NDUFA12 mutations as a new cause of Leigh syndrome.