NDST3 Antibodies

AND NDST3 ELISA kits, NDST3 Proteins

Many biological assays use antibodies to detect NDST3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NDST3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NDST3 antibodies...

We validate the specificity of these antibodies to NDST3 by testing them on tissues known to express NDST3 positively and negatively. Browse below to find the NDST3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NDST3 Infographic by Boster Bio

All NDST3 Products

Product

Figures

Specificity

Applications

Price

NDST3 (NM_004784) Human Recombinant Protein

$1249
Cat # PROTO95803
20 µg

NDST3 (NM_004784) Human Over-expression Lysate

Human

$960
Cat # LS009348
100 µg

NDST3 Overview

Facts about Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3.

NDST3 3D structure. Source: alphafold

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 (NDST3)

Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later alterations in heparin biosynthesis.

Has high deacetylase activity but low sulfotransferase activity. .

Gene Information

Human
Gene Name:	NDST3
Uniprot:	O95803
Entrez:	9348

Family

Belongs to:

sulfotransferase 1 family

Alternative Names

bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3; EC 2.8.2.8; GlcNAc N-deacetylase/ N-sulfotransferase 3; Glucosaminyl N-deacetylase/N-sulfotransferase 3; hNDST-3; HSST3MGC130028; MGC130029; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3; NDST-3; N-heparan sulfate sulfotransferase 3; N-HSST 3

Molecular Weight

Mass (kDA):
100.902 kDA

Genomic Context


Human

Location:	4q26
Sequence:	4; NC_000004.12 (118033322..118258945)

Tissue Specificity

Expressed in brain, kidney, liver, fetal and adult lung, adult pancreas, placenta, fetal spleen and fetal thymus. Not detected in adult/ fetal heart and skeletal muscle.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Exostoses
Inflammation
Chimera Disorder
Growth Arrest

Pathways

Sulfation
Reverse Transcription
Cell Proliferation
Lung Development
Osteoblast Proliferation

PTMs

Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NDST3

References

PMID: 9915799 by Aikawa J., et al. Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family.