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- Table of Contents
1 Citations 1 Q&As
Facts about Protein NDRG2.
Contributes to the regulation of the Wnt signaling pathway.
Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor.May be involved in dendritic cell and neuron differentiation (By similarity). .
Mouse | |
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Gene Name: | Ndrg2 |
Uniprot: | Q9QYG0 |
Entrez: | 29811 |
Belongs to: |
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NDRG family |
DKFZp781G1938; FLJ25522; KIAA1248cytoplasmic protein Ndr1; NDR1-related protein NDR2; NDRG family member 2; protein NDRG2; Protein Syld709613; syld709613 protein; SYLDN-myc downstream regulator 2
Mass (kDA):
40.789 kDA
Mouse | |
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Location: | 14|14 C1 |
Sequence: | 14; |
Expressed at highest levels in brain, heart and liver, and at lower levels in kidney, colon, skeletal muscle, adrenal gland, ovary and uterus (at protein level).
PMID: 10581191 by Okuda T., et al. Identification of new genes ndr2 and ndr3 which are related to Ndr1/RTP/Drg1 but show distinct tissue specificity and response to N- myc.
PMID: 15461589 by Murray J.T., et al. Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3.
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