Necdin Antibodies

AND NDN ELISA kits, Necdin Proteins

Many biological assays use antibodies to detect Necdin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Necdin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Necdin antibodies...

We validate the specificity of these antibodies to Necdin by testing them on tissues known to express NDN positively and negatively. Browse below to find the NDN antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NDN Infographic by Boster Bio

All NDN Products

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Specificity

Applications

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Necdin (NDN) (NM_002487) Human Recombinant Protein

$813
Cat # PROTQ99608
20 µg

Anti-Necdin (NDN) Mouse Monoclonal Antibody [Clone ID: OTI5D1]

+15

Human

IF, IHC, WB

$523
Cat # M04394
100 µl

Necdin (NDN) (NM_002487) Human Over-expression Lysate

Human

$628
Cat # LS004692
100 µg

NDN Overview

Facts about Necdin.

NDN 3D structure. Source: alphafold

Necdin (NDN)

Growth suppressor that eases the entry of the cell into cell cycle arrest. Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle- boosting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F.

Necdin also interacts with p53 and works in an additive manner to inhibit cell growth. Functions also as transcription factor and binds directly to specific guanosine-rich DNA sequences (By similarity).

Gene Information

Human
Gene Name:	NDN
Uniprot:	Q99608
Entrez:	4692

Family

Belongs to:

No superfamily

Alternative Names

HsT16328; necdin (mouse) homolog; necdin homolog (mouse); necdin; PWCR

Molecular Weight

Mass (kDA):
36.086 kDA

Genomic Context


Human

Location:	15q11.2
Sequence:	15; NC_000015.10 (23685400..23687305, complement)

Tissue Specificity

Almost ubiquitous. Detected in fetal brain, lung, liver and kidney; in adult heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon. Not detected in peripheral blood leukocytes. In brain, restricted to post- mitotic neurons.