Norrin Antibodies

AND NDP ELISA kits, Norrin Proteins

Many biological assays use antibodies to detect Norrin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Norrin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Norrin antibodies...

We validate the specificity of these antibodies to Norrin by testing them on tissues known to express NDP positively and negatively. Browse below to find the NDP antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NDP Infographic by Boster Bio

All NDP Products

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Product

Figures

Specificity

Applications

Price

Anti-Norrin NDP Antibody

Human

ELISA, ICC, WB

$449
Cat # A01045
0.1 mg

Anti-Norrin NDP Antibody

Mouse

$405
Cat # A01045-1
100ul

Human Norrin Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTQ00604
Starting from 10ug

NDP Overview

Facts about Norrin.

NDP 3D structure. Source: alphafold

Norrin (NDP)

Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and triggering LEF/TCF-mediated transcriptional programs.

Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, implying the occurrence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation.

Gene Information

Human
Gene Name:	NDP
Uniprot:	Q00604
Entrez:	4693

Family

Belongs to:

No superfamily

Alternative Names

EVR2; exudative vitreoretinopathy 2 (X-linked); FEVR; ND; NDP; Norrie disease (pseudoglioma); Norrie disease protein; Norrin; X-linked exudative vitreoretinopathy 2 protein