Cytoplasmic protein NCK2 Antibodies

AND NCK2 ELISA kits, Cytoplasmic protein NCK2 Proteins

Many biological assays use antibodies to detect Cytoplasmic protein NCK2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytoplasmic protein NCK2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytoplasmic protein NCK2 antibodies...

We validate the specificity of these antibodies to Cytoplasmic protein NCK2 by testing them on tissues known to express NCK2 positively and negatively. Browse below to find the NCK2 antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NCK2 Infographic by Boster Bio

All NCK2 Products

Product

Figures

Specificity

Applications

Price

Anti-NCK2/Nck Beta Antibody

13 Q&As

Human

IHC

$360
Cat # A04036
100 µl

Anti-Nck2 (I364) Antibody

Human, Mouse, Rat

IHC

$405
Cat # A04036-1
100ul

Anti-Cytoplasmic protein NCK2 NCK2 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A04036-2
100ul

Nck beta (NCK2) (NM_001004720) Human Recombinant Protein

$1249
Cat # PROTO43639
20 µg

Anti-Nck beta (NCK2) Mouse Monoclonal Antibody [Clone ID: OTI4H7]

Human, Mouse, Rat

$523
Cat # M04036
100 µl

Anti-Nck2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M04036-1
100 μl/vial

Nck beta (NCK2) (NM_003581) Human Over-expression Lysate

Human

$628
Cat # LS008440
100 µg

NCK2 Overview

Facts about Cytoplasmic protein NCK2.

NCK2 3D structure. Source: alphafold

Cytoplasmic protein NCK2 (NCK2)

Adapter protein that associates with tyrosine- phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1.

Plays a role in ELK1- dependent transcriptional activation in response to activated Ras signaling. .

Gene Information

Human
Gene Name:	NCK2
Uniprot:	O43639
Entrez:	8440

Family

Belongs to:

No superfamily

Alternative Names

GRB4; NCK adaptor protein 2cytoplasmic protein NCK2; Nck-2; NCKbeta; noncatalytic region of tyrosine kinase, beta; SH2/SH3 adaptor protein NCK-beta

Molecular Weight

Mass (kDA):
42.915 kDA

Genomic Context


Human

Location:	2q12.2
Sequence:	2; NC_000002.12 (105744649..105894274)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. Endoplasmic reticulum.

Diseases

Tissue Adhesions
Neoplasms
Malignant Neoplasms
Neoplasm Metastasis
Melanoma
Nervousness
Wiskott-aldrich Syndrome
Cell Invasion
Cell Transformation, Neoplastic
Skin Wound
Cardiac Hypertrophy

Glaucoma, Open-angle
Neoplasm Invasiveness
Endoplasmic Reticulum Stress
Cardiovascular Diseases
Tumor Angiogenesis
Pathologic Neovascularization

Pathways

Cell Migration
Localization
Cell Adhesion
Cell Motility
Cell Proliferation
Rna Interference
Wound Healing
Actin Nucleation
Transport
Ras Protein Signal Transduction
Cell Activation
Response To Wounding
Cellular Homeostasis

T Cell Activation
Proteolysis
Virulence
Fibroblast Migration
Cytoskeleton Organization
Chemotaxis
Translation

PTMs

Phosphorylation

Cleavage

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NCK2

References

PMID: 9737977 by Chen M., et al. Identification of Nck family genes, chromosomal localization, expression, and signaling specificity.

PMID: 9843575 by Tu Y., et al. Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways.