This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
, No Gclids
NCAPG Antibodies
AND NCAPG ELISA kits, NCAPG Proteins
Many biological assays use antibodies to detect NCAPG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NCAPG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NCAPG antibodies...
Previous: Septin9
Next: Chp1
NCAPG Infographic by Boster Bio
All NCAPG Products
Product
Figures
Specificity
Applications
Price
NCAPG Overview
Facts about Condensin complex subunit 3.
Condensin complex subunit 3 (NCAPG)
Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | NCAPG |
| Uniprot: | Q9BPX3 |
| Entrez: | 64151 |
Family
| Belongs to: |
|---|
| CND3 (condensin subunit 3) family |
Alternative Names
CAP-G; CAPGHCAP-G; CHCG; chromosome condensation protein G; Chromosome-associated protein G; condensin complex subunit 3; Condensin subunit CAP-G; FLJ12450; hCAP-G; Melanoma antigen NY-MEL-3; MGC126525; Non-SMC condensin I complex subunit G; non-SMC condensin I complex, subunit G; NYMEL3; NY-MEL-3; XCAP-G homolog
Molecular Weight
Mass (kDA):
114.334 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4p15.31 |
| Sequence: | 4; NC_000004.12 (17810942..17844865) |
Tissue Specificity
Highly expressed in testis.
Subcellular Localizations
Nucleus. Cytoplasm. Chromosome. In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase
Diseases
- Dysequilibrium Syndrome
- Cell Invasion
- Stillbirth
- Neoplasm Metastasis
- Malignant Neoplasms
- Neoplasms
- Primary Neoplasm
- Melanoma
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- NCAPH
Pathways
- Chromosome Condensation
- Methylation
- Dna Replication
- Translation
- Melanocyte Differentiation
- Cell Cycle
- Mitosis
PTMs
- Phosphorylation
Research Areas
- Cell Cycle and Replication
- DNA Repair
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NCAPG
bosterbio.com/bosterbio-gene-info-cards/NCAPG
References
PMID: 10910072 by Jaeger D., et al. Serological cloning of a melanocyte rab guanosine 5'-triphosphate- binding protein and a chromosome condensation protein from a melanoma complementary DNA library.
PMID: 11136719 by Kimura K., et al. Chromosome condensation by a human condensin complex in Xenopus egg extracts.