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- Table of Contents
Facts about N-acetylaspartate synthetase.
Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake.
Mouse | |
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Gene Name: | Nat8l |
Uniprot: | Q3UGX3 |
Entrez: | 269642 |
Belongs to: |
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camello family |
Camello-like protein 3; CML3; DKFZp434B0650; DKFZp566H184; EC 2.3.1.17; FLJ37478; Hcml3; MGC117272; NAA synthetase; N-acetyltransferase 8-like (GCN5-related, putative); N-acetyltransferase 8-like protein; N-acetyltransferase 8-like; NAT8-LIKE
Mass (kDA):
32.777 kDA
Mouse | |
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Location: | 5|5 B2 |
Sequence: | 5; |
Expressed in brain, kidney, liver and spleen. In brain, present in neurons but not in astrocytes (at protein level). Expressed in brain, thymus and spleen.
PMID: 17626222 by Niwa M., et al. A novel molecule 'Shati' is involved in methamphetamine-induced hyperlocomotion, sensitization, and conditioned place preference.
PMID: 19014384 by Niwa M., et al. A novel molecule 'shati' increases dopamine uptake via the induction of tumor necrosis factor-alpha in pheochromocytoma-12 cells.