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- Table of Contents
Facts about Nucleosome assembly protein 1-like 4.
Human | |
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Gene Name: | NAP1L4 |
Uniprot: | Q99733 |
Entrez: | 4676 |
Belongs to: |
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nucleosome assembly protein (NAP) family |
hNAP2; MGC4565; NAP-2; NAP2L; NAP2NAP1L4b; nucleosome assembly protein 1-like 4; nucleosome assembly protein 1-like 4b; Nucleosome assembly protein 2
Mass (kDA):
42.823 kDA
Human | |
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Location: | 11p15.4 |
Sequence: | 11; NC_000011.10 (2944437..2992329, complement) |
Ubiquitous. Biallelically expressed in fetal and adult tissues. Highest levels in testis.
Nucleus. Cytoplasm. Present in the cytoplasm and excluded from the nucleus during G0/G1 phase, then relocates to the nucleus by the time cells are in S phase (PubMed:9325046). Phosphorylated form localizes in the cytoplasm during the G0/G1 transition, whereas dephosphorylation leads to relocalization into the nucleus at the G1/S-boundary (PubMed:10764593).
PMID: 8923002 by Hu R.-J., et al. A novel human homologue of yeast nucleosome assembly protein, 65 kb centromeric to the p57KIP2 gene, is biallelically expressed in fetal and adult tissues.
PMID: 9325046 by Rodriguez P., et al. Functional characterization of human nucleosome assembly protein-2 (NAP1L4) suggests a role as a histone chaperone.