Nanos homolog 1 Antibodies

AND Nanos1 ELISA kits, Nanos homolog 1 Proteins

Many biological assays use antibodies to detect Nanos homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nanos homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nanos homolog 1 antibodies...

We validate the specificity of these antibodies to Nanos homolog 1 by testing them on tissues known to express Nanos1 positively and negatively. Browse below to find the Nanos1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Nanos1 Infographic by Boster Bio

All Nanos1 Products

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Anti-Nanos homolog 1 Nanos1 Antibody

Human

ELISA, IF, IHC-P, WB

$449
Cat # A07276
0.1 mg

Anti-Nanos homolog 1 Nanos1 Antibody

Human, Mouse, Rat

ELISA, IF, WB

$449
Cat # A07276-1
0.1 mg

NANOS1 (NM_199461) Human Over-expression Lysate

Human

$628
Cat # LS340719
100 µg

Nanos1 Overview

Facts about Nanos homolog 1.

Nanos homolog 1 (Nanos1)

May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that partners with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin.

Up-regulates the creation of MMP14 to promote tumor cell invasion (By similarity). Not essential for normal development.

Gene Information

Mouse
Gene Name:	Nanos1
Uniprot:	Q80WY3
Entrez:	332397

Family

Belongs to:

nanos family

Alternative Names

nanos homolog 1 (Drosophila); nanos homolog 1; NOS-1; NOS1EC_Rep1a

Molecular Weight

Mass (kDA):
28.151 kDA

Genomic Context


Mouse

Location:	19\|19 D3
Sequence:	19;

Tissue Specificity

Expressed in the oocyte. Transiently expressed in eight-cell embryos. At 12.5 dpc, it is re-expressed in the central nervous system and the expression continues in the adult brain, in which the hippocampal formation is the predominant region. Expressed in the seminiferous tubules of mature testis, but not in the primordial germ cells.

Diseases

Cell Invasion
Congenital Abnormality
Tissue Adhesions
Neoplasm Invasiveness
Malignant Neoplasms
Neoplasms
Abnormal Degeneration
Neoplasm Metastasis
Disease Of Adrenal Medulla
Epithelioma
Lung Neoplasms
Tumor Progression
Malignant Neoplasm Of Breast

Muscular Dystrophy, Duchenne
Protrusion
Dystrophy
Carcinoma
Nervousness
Testicular Germ Cell Tumor
Pituitary Diseases

Pathways

Cell Development
Germ Cell Development
Translation
Localization
Cell Migration
Fertilization
Cell Differentiation
Rna Localization
Cell Cycle
Oogenesis
Transport
Cell Adhesion
Epithelial Cell-cell Adhesion

Cell Proliferation
G1 Phase
Snare Complex Assembly
Epiboly
Spermatogenesis
Sex Differentiation
Germ Cell Proliferation

PTMs

Cleavage

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nanos1

References

PMID: 12834871 by Haraguchi S., et al. nanos1: a mouse nanos gene expressed in the central nervous system is dispensable for normal development.