NAA80 Antibodies

AND NAA80 ELISA kits, NAA80 Proteins

Many biological assays use antibodies to detect NAA80, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NAA80 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NAA80 antibodies...

We validate the specificity of these antibodies to NAA80 by testing them on tissues known to express NAA80 positively and negatively. Browse below to find the NAA80 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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NAA80 Infographic by Boster Bio

All NAA80 Products

Product

Figures

Specificity

Applications

Price

FUS2 (NAT6) (NM_012191) Human Recombinant Protein

$1249
Cat # PROTQ93015
20 µg

FUS2 (NAT6) (NM_012191) Human Over-expression Lysate

Human

$628
Cat # LS024142
100 µg

NAA80 Overview

Facts about N-alpha-acetyltransferase 80.

NAA80 3D structure. Source: alphafold

N-alpha-acetyltransferase 80 (NAA80)

N-alpha-acetyltransferase that specifically mediates the acetylation of the acidic amino terminus of processed forms of beta- and gamma-actin (ACTB and ACTG, respectively) (PubMed:30028079, PubMed:29581253). N-terminal acetylation of processed beta- and gamma-actin modulates actin filament depolymerization and elongation (PubMed:29581253).

In vivo, preferentially shows N-terminal acetyltransferase activity towards acid N-terminal sequences starting with Asp-Asp-Asp and Glu-Glu-Glu (PubMed:30028079, PubMed:29581253). In vitro, shows high activity towards Met-Asp-Glu-Leu and Met-Asp-Asp-Asp (PubMed:10644992, PubMed:29581307).

Gene Information

Human
Gene Name:	NAA80
Uniprot:	Q93015
Entrez:	24142

Family

Belongs to:

acetyltransferase family

Alternative Names

FUS-2; FUS2EC 2.3.1.-; N-acetyltransferase 6 (GCN5-related); N-acetyltransferase 6; Protein fus-2; Protein fusion-2

Molecular Weight

Mass (kDA):
31.445 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (50296402..50299405, complement)

Tissue Specificity

Strongly expressed in heart and skeletal muscle, followed by brain and pancreas, with weak expression in kidney, liver, and lung and no expression in placenta.

Subcellular Localizations

Cytoplasm, cytosol.

Diseases

Malignant Neoplasms
Neoplasms
Nasopharyngeal Neoplasms
Malignant Neoplasm Of Nasopharynx
Endemic Diseases
Carcinoma

Cancer Of Nasopharynx

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NAA80

References

PMID: 10644992 by Zegerman P., et al. The putative tumour suppressor Fus-2 is an N-acetyltransferase.

PMID: 11085536 by Lerman M.I., et al. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes.