Myosin-7 Antibodies

AND MYH7 ELISA kits, Myosin-7 Proteins

Many biological assays use antibodies to detect Myosin-7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myosin-7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myosin-7 antibodies...

We validate the specificity of these antibodies to Myosin-7 by testing them on tissues known to express MYH7 positively and negatively. Browse below to find the MYH7 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYH7 Infographic by Boster Bio

All MYH7 Products

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Anti-Myosin(Skeletal, Slow) Myh7 Antibody (Monoclonal, NOQ7.5.4D)

2 Citations 7 Q&As

Human, Monkey, Mouse, Rat

IHC, WB

$370
Cat # MA1064
100 μg/vial

MYH7 Overview

Facts about Myosin-7.

MYH7 3D structure. Source: alphafold

Myosin-7 (MYH7)

Myosins are actin-based motor molecules with ATPase activity necessary for muscle contraction. Types regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile component of skeletal and cardiac muscle.

Gene Information

Human
Gene Name:	MYH7
Uniprot:	P12883
Entrez:	4625

Family

Belongs to:

TRAFAC class myosin-kinesin ATPase superfamily

Alternative Names

cardiac muscle beta isoform; CMD1S; CMD1SMGC138376; CMH1; DKFZp451F047; MGC138378; MPD1; MYH7; MYHCB; MyHC-beta; myhc-slow; myopathy, distal 1; myosin heavy chain (AA 1-96); myosin, heavy chain 7, cardiac muscle, beta; myosin, heavy polypeptide 7, cardiac muscle, beta; Myosin-7; rhabdomyosarcoma antigen MU-RMS-40.7A; SPMD; SPMM

Molecular Weight

Mass (kDA):
223.097 kDA

Genomic Context


Human

Location:	14q11.2
Sequence:	14; NC_000014.9 (23412740..23435677, complement)

Tissue Specificity

Both wild type and variant Gln-403 are detected in skeletal muscle (at protein level).

Subcellular Localizations

Cytoplasm, myofibril. Cytoplasm, myofibril, sarcomere. Thick filaments of the myofibrils.

Diseases

Cardiomyopathies
Hypertrophy
Hypertrophic Cardiomyopathy
Cardiomyopathy, Hypertrophic, Familial
Myopathy
Sudden Cardiac Death
Cardiomyopathy, Dilated
Cardiac Death
Heart Failure
Left Ventricular Hypertrophy
Cardiomyopathy, Familial Idiopathic
Distal Muscular Dystrophies

Sudden Death
Heart Diseases
Weakness
Cardiac Hypertrophy
Muscle Weakness
Malignant Paraganglionic Neoplasm
Hereditary Diseases

Interacting Proteins

KXD1
LRRC39

Pathways

Pathogenesis
Localization
Transport
Mrna Splicing
Translation
Metaphase
Innervation
Cell Migration
Fertilization
Regulation Of Gene Expression
Cardiac Conduction
Cell Motility
Cell Differentiation

Lipid Storage
Myoblast Differentiation
Chromatin Remodeling
Myoblast Fusion
Response To Stress
Myosin Filament Assembly
Energy Homeostasis

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYH7

References

PMID: 2249844 by Jaenicke T., et al. The complete sequence of the human beta-myosin heavy chain gene and a comparative analysis of its product.

PMID: 2362820 by Liew C.-C., et al. Complete sequence and organization of the human cardiac beta-myosin heavy chain gene.

3 Publications of Boster Myosin-7 Antibodies & ELISA Kits

PubMed ID: -, Yan X,Niu Q,Gao X,Shen S,He N,Wang H,Fang R,Gao Y,Chang H.2021.Differential prot...
PubMed ID: 28455747, Wang LP, Fan SJ, Li SM, Wang XJ, Gao JL, Yang XH. Pflugers Arch. 2017 Apr 28. do...
PubMed ID: 23640900, Nie Yw, Ding Xb, Ge Xg, Fan Hl, Liu Zw, Guo H. Cell Biol Int. 2013 Sep;37(9):972...

*More publications can be found for each product on its corresponding product page