Mei4 Antibodies

AND Mei4 ELISA kits, Mei4 Proteins

Many biological assays use antibodies to detect Mei4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mei4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mei4 antibodies...

We validate the specificity of these antibodies to Mei4 by testing them on tissues known to express Mei4 positively and negatively. Browse below to find the Mei4 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Mei4 Infographic by Boster Bio

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Mei4 Overview

Facts about Meiosis-specific protein MEI4.

Meiosis-specific protein MEI4 (Mei4)

Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination (PubMed:20551173, PubMed:25795304, PubMed:27723721). Probably acts by forming a complex with IHO1/CCDC36 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to guarantee completion of synapsis (PubMed:27723721).

Gene Information

Mouse
Gene Name:	Mei4
Uniprot:	Q8BRM6
Entrez:	75033

Family

Belongs to:

MEI4L family

Alternative Names

Meiosis-specific protein MEI4

Molecular Weight

Mass (kDA):
44.471 kDA

Genomic Context


Mouse

Location:	9\|9 E1
Sequence:	9;

Tissue Specificity

Expressed in adult testis and brain and in embryonic ovary.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Mei4

References

PMID: 20551173 by Kumar R., et al. Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice.

PMID: 25795304 by Kumar R., et al. MEI4 - a central player in the regulation of meiotic DNA double- strand break formation in the mouse.