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- Table of Contents
1 Citations 9 Q&As
Facts about Mannose-binding protein C.
Binds to late apoptotic cells, and to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Human | |
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Gene Name: | MBL2 |
Uniprot: | P11226 |
Entrez: | 4153 |
Belongs to: |
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No superfamily |
COLEC1; COLEC1collectin-1; Collectin-1; HSMBPC; Mannan-binding protein; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin (protein C) 2, soluble; Mannose-binding lectin; mannose-binding protein C; MBL; MBL2; MBL2D; MBLmannan-binding lectin; MBP; MBP1; MBP1mannose-binding lectin 2, soluble (opsonic defect); MBP-C; MGC116832; MGC116833
Mass (kDA):
26.144 kDA
Human | |
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Location: | 10q21.1 |
Sequence: | 10; NC_000010.11 (52765380..52772784, complement) |
Plasma protein produced mainly in the liver.
Secreted.
PMID: 2450948 by Ezekowitz R.A.B., et al. A human mannose-binding protein is an acute-phase reactant that shares sequence homology with other vertebrate lectins.
PMID: 2477486 by Sastry K., et al. The human mannose-binding protein gene. Exon structure reveals its evolutionary relationship to a human pulmonary surfactant gene and localization to chromosome 10.
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