MAN1A2 Antibodies

AND MAN1A2 ELISA kits, MAN1A2 Proteins

Many biological assays use antibodies to detect MAN1A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MAN1A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MAN1A2 antibodies...

We validate the specificity of these antibodies to MAN1A2 by testing them on tissues known to express MAN1A2 positively and negatively. Browse below to find the MAN1A2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MAN1A2 Infographic by Boster Bio

All MAN1A2 Products

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Anti-MAN1A2 Antibody

Human, Mouse

IHC, WB

$405
Cat # A11639
100ul

MAN1A2 Overview

Facts about Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB.

MAN1A2 3D structure. Source: alphafold

Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (MAN1A2)

Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).

Gene Information

Human
Gene Name:	MAN1A2
Uniprot:	O60476
Entrez:	10905

Family

Belongs to:

glycosyl hydrolase 47 family

Alternative Names

Alpha-1,2-mannosidase IB; EC 3.2.1.113; MAN1Balpha1,2-mannosidase; Mannosidase alpha class 1A member 2; mannosidase, alpha, class 1A, member 2; mannosyl-oligosaccharide 1,2-alpha-mannosidase IB; Processing alpha-1,2-mannosidase IB

Molecular Weight

Mass (kDA):
73.004 kDA

Genomic Context


Human

Location:	1p12
Sequence:	1; NC_000001.11 (117367393..117528872)

Tissue Specificity

Highest levels of expression in placenta and testis.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein.

Diseases

Inflammatory Disorder
Inflammation
Tissue Adhesions
Atherosclerosis

Pathways

N-glycan Processing

PTMs

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MAN1A2

References

PMID: 9592125 by Tremblay L.O., et al. Molecular cloning, chromosomal mapping and tissue-specific expression of a novel human alpha-1,2-mannosidase gene involved in N-glycan maturation.