TRAFD1 Antibodies

AND TRAFD1 ELISA kits, TRAFD1 Proteins

Many biological assays use antibodies to detect TRAFD1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TRAFD1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TRAFD1 antibodies...

We validate the specificity of these antibodies to TRAFD1 by testing them on tissues known to express TRAFD1 positively and negatively. Browse below to find the TRAFD1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TRAFD1 Infographic by Boster Bio

All TRAFD1 Products

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Product

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Specificity

Applications

Price

Anti-TRAFD1 Antibody

Human

$405
Cat # A05204
100ul

Anti-TRAFD1 Mouse Monoclonal Antibody [Clone ID: OTI3E8]

Human

$523
Cat # M05204
100 µl

TRAFD1 Overview

Facts about TRAF-type zinc finger domain-containing protein 1.

TRAFD1 3D structure. Source: alphafold

TRAF-type zinc finger domain-containing protein 1 (TRAFD1)

Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways.

May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).

Gene Information

Human
Gene Name:	TRAFD1
Uniprot:	O14545
Entrez:	10906

Family

Belongs to:

No superfamily

Alternative Names

FLN29FLN29 gene product; Protein FLN29; TRAF-type zinc finger domain containing 1; TRAF-type zinc finger domain-containing protein 1

Molecular Weight

Mass (kDA):
64.841 kDA

Genomic Context


Human

Location:	12q24.13
Sequence:	12; NC_000012.12 (112125545..112153604)

Diseases

Virus Diseases
Septic Shock
Malignant Neoplasms
Stomatitis
Vesicular Stomatitis

Interacting Proteins

HTT
NGLY1

Pathways

Programmed Cell Death
Cell Death

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TRAFD1

References

PMID: 16221674 by Mashima R., et al. FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling.