Myocardin Antibodies

AND MYOCD ELISA kits, Myocardin Proteins

Many biological assays use antibodies to detect Myocardin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myocardin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myocardin antibodies...

We validate the specificity of these antibodies to Myocardin by testing them on tissues known to express MYOCD positively and negatively. Browse below to find the MYOCD antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYOCD Infographic by Boster Bio

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Anti-MYCD MYOCD Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A03542
100ul

MYOCD Overview

Facts about Myocardin.

MYOCD 3D structure. Source: alphafold

Myocardin (MYOCD)

Smooth muscle cells (SM) and cardiac muscle tissues - specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes.

Plays a vital role in cardiogenesis and distinction of the smooth muscle cell lineage (myogenesis) (By similarity). .

Gene Information

Human
Gene Name:	MYOCD
Uniprot:	Q8IZQ8
Entrez:	93649

Family

Belongs to:

No superfamily

Alternative Names

BSAC2A; MYCD; Myocardin; MYOCD; Srfcp

Molecular Weight

Mass (kDA):
101.997 kDA

Genomic Context


Human

Location:	17p12
Sequence:	17; NC_000017.11 (12665890..12768949)

Tissue Specificity

Expressed in heart, aorta, and in smooth muscle cell-containing tissues: stomach, bladder, small intestine, colon, lung, placenta and uterus. Very faint expression in prostate and skeletal muscle.

Subcellular Localizations

Nucleus.

Diseases

Heart Failure
Alzheimer's Disease
Neoplasms
Arterial Injury
Impaired Cognition
Vascular Diseases
Dementia
Senile Cerebral Amyloid Angiopathy
Heart Diseases
Hypertrophy
Cardiovascular Diseases
Congenital Heart Defects
Cerebrovascular Accident

Cerebral Amyloid Angiopathy
Atherosclerosis
Cholangiocarcinoma
Undifferentiated (embryonal) Sarcoma
Muscular Dystrophy, Duchenne
Hypoxia
Sarcoma

Interacting Proteins

GOPC
SRF

Pathways

Cell Differentiation
Pathogenesis
Transport
Vascular Smooth Muscle Cell Differentiation
Cell Proliferation
Muscle Cell Differentiation
Programmed Cell Death
Cell Death
Heart Development
Smooth Muscle Cell Differentiation
Cell Adhesion
Cell Migration
Stem Cell Differentiation

Wnt Receptor Signaling Pathway
Sarcomerogenesis
Regeneration
Ureter Development
Dedifferentiation
Cell Growth
Angiogenesis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYOCD

References

PMID: 12397177 by Wang D.-Z., et al. Potentiation of serum response factor activity by a family of myocardin-related transcription factors.

PMID: 12640126 by Du K.L., et al. Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation.