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- Table of Contents
Facts about Myosin-IIIb.
Plays an essential role in the early steps of cochlear hair bundle morphogenesis. Influences the lengths and number of stereocilia to be produced and limits the development of microvilli inside the forming auditory hair follicles thereby contributing to the architecture of the hair bundle, including its staircase pattern.
Human | |
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Gene Name: | MYO3B |
Uniprot: | Q8WXR4 |
Entrez: | 140469 |
Belongs to: |
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No superfamily |
EC 2.7.11; EC 2.7.11.1; myosin IIIB; myosin-IIIb
Mass (kDA):
151.829 kDA
Human | |
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Location: | 2q31.1 |
Sequence: | 2; NC_000002.12 (170178147..170655167) |
Expressed in retina, kidney and testis.
Cytoplasm, cytoskeleton. Cell projection, stereocilium.
PMID: 11991710 by Dose A.C., et al. A class III myosin expressed in the retina is a potential candidate for Bardet-Biedl syndrome.