Myosin-IIIa Antibodies

AND MYO3A ELISA kits, Myosin-IIIa Proteins

Many biological assays use antibodies to detect Myosin-IIIa, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myosin-IIIa in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myosin-IIIa antibodies...

We validate the specificity of these antibodies to Myosin-IIIa by testing them on tissues known to express MYO3A positively and negatively. Browse below to find the MYO3A antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYO3A Infographic by Boster Bio

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Anti-Myosin-IIIa MYO3A Antibody

Human, Mouse

ELISA, WB

$380
Cat # A07856
100ul

MYO3A Overview

Facts about Myosin-IIIa.

MYO3A 3D structure. Source: alphafold

Myosin-IIIa (MYO3A)

Probable actin-based motor using a protein kinase activity. Probably plays a role in hearing and vision (PubMed:12032315).

Required for normal cochlear hair package development and hearing. Plays an important role in the early measures of cochlear hair bundle morphogenesis.

Gene Information

Human
Gene Name:	MYO3A
Uniprot:	Q8NEV4
Entrez:	53904

Family

Belongs to:

No superfamily

Alternative Names

deafness, autosomal recessive 30; DFNB30; EC 2.7.11; EC 2.7.11.1; myosin IIIA; myosin-IIIa

Molecular Weight

Mass (kDA):
186.208 kDA

Genomic Context


Human

Location:	10p12.1
Sequence:	10; NC_000010.11 (25934229..26212536)

Tissue Specificity

Strongest expression in retina, retinal pigment epithelial cells, cochlea and pancreas.

Subcellular Localizations

Cytoplasm, cytoskeleton. Cytoplasm. Cell projection, filopodium tip. Cell projection, stereocilium. Increased localization at the filodium tip seen in the presence of MORN4.

Diseases

Complete Hearing Loss
Retinal Degeneration
Malignant Neoplasms
Deafness Congenital
Mood Disorders
Psychiatric Diagnosis
Malignant Neoplasm Of Urinary Bladder
Neoplasm/cancer Invasiveness
Neoplasms
Colorectal Cancer
Retinal Diseases
Rheumatoid Arthritis

Bladder Neoplasm
Anxiety Disorders
Nerve Degeneration
Protrusion
Bardet-biedl Syndrome
Autoimmune Diseases
Arthritis

Pathways

Localization
Cellular Localization
Transport
Methylation
Dna Hypermethylation
Dna Methylation

Phototransduction

PTMs

Phosphorylation

Methylation

Dephosphorylation

Research Areas

Protein Kinase
Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYO3A

References

PMID: 10936054 by Dose A.C., et al. Cloning and chromosomal localization of a human class III myosin.

PMID: 12032315 by Walsh T., et al. From flies' eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30.