MYO18B Antibodies

AND MYO18B ELISA kits, MYO18B Proteins

Many biological assays use antibodies to detect MYO18B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MYO18B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MYO18B antibodies...

We validate the specificity of these antibodies to MYO18B by testing them on tissues known to express MYO18B positively and negatively. Browse below to find the MYO18B antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYO18B Infographic by Boster Bio

All MYO18B Products

Product

Figures

Specificity

Applications

Price

Anti-MY18B MYO18B Antibody

Human

IHC

$380
Cat # A07278
100ul

MYO18B Overview

Facts about Unconventional myosin-XVIIIb.

MYO18B 3D structure. Source: alphafold

Unconventional myosin-XVIIIb (MYO18B)

May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, could be involved in the regulation of muscle specific genes. May play a role in the control of tumor growth and progression; restored MYO18B expression in lung cancer cells inhibits anchorage-independent growth.

Gene Information

Human
Gene Name:	MYO18B
Uniprot:	Q8IUG5
Entrez:	84700

Family

Belongs to:

TRAFAC class myosin-kinesin ATPase superfamily

Alternative Names

Unconventional myosin-XVIIIb

Molecular Weight

Mass (kDA):
285.215 kDA

Genomic Context


Human

Location:	22q12.1
Sequence:	22; NC_000022.11 (25742133..26063847)

Tissue Specificity

Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.

Subcellular Localizations

Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.

Diseases

Klippel-Feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism (KFS4)

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYO18B

References

PMID: 12209013 by Nishioka M., et al. MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer.

PMID: 12547197 by Salamon M., et al. Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation.