MYLK2 Antibodies

AND MYLK2 ELISA kits, MYLK2 Proteins

Many biological assays use antibodies to detect MYLK2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MYLK2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MYLK2 antibodies...

We validate the specificity of these antibodies to MYLK2 by testing them on tissues known to express MYLK2 positively and negatively. Browse below to find the MYLK2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYLK2 Infographic by Boster Bio

All MYLK2 Products

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Product

Figures

Specificity

Applications

Price

Anti-MYLK2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A10258
100ul

MYLK2 (NM_033118) Human Recombinant Protein

$1062
Cat # PROTQ9H1R3
20 µg

MYLK2 (NM_033118) Human Over-expression Lysate

Human

$960
Cat # LS085366
100 µg

MYLK2 Overview

Facts about Myosin light chain kinase 2, skeletal/cardiac muscle.

MYLK2 3D structure. Source: alphafold

Myosin light chain kinase 2, skeletal/cardiac muscle (MYLK2)

Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a particular serine at the N- terminus of a myosin light chain.

Gene Information

Human
Gene Name:	MYLK2
Uniprot:	Q9H1R3
Entrez:	85366

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.11; EC 2.7.11.18; KMLC; MLCK2MLCK; myosin light chain kinase 2; myosin light chain kinase 2, skeletal/cardiac muscle; skeletal muscle; skMLCK

Molecular Weight

Mass (kDA):
64.685 kDA

Genomic Context


Human

Location:	20q11.21
Sequence:	20; NC_000020.11 (31819356..31834684)

Tissue Specificity

Heart and skeletal muscles. Increased expression in the apical tissue compared to the interventricular septal tissue.

Subcellular Localizations

Cytoplasm. Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.

Diseases

Neoplasms
Malignant Neoplasms
Adenocarcinoma
Stenosis
Tetanus
Heart Failure
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Lung
Carcinoma

Myocardial Infarction
Muscle Twitch
Leukemia
Colorectal Cancer

Interacting Proteins

MEF2C
TRIM54

Pathways

Egg Activation
Mitosis
Fertilization
Immune Response
Dna Repair
Muscle Contraction
Ovulation
Anaphase
Cytokinesis
Telophase

Cell Cycle
Skeletal Muscle Contraction
Sarcomere Organization
Pathogenesis
Exocytosis

PTMs

Phosphorylation

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYLK2

References

PMID: 11733062 by Davis J.S., et al. The overall pattern of cardiac contraction depends on a spatial gradient of myosin regulatory light chain phosphorylation.