Myb-binding protein 1A Antibodies

AND MYBBP1A ELISA kits, Myb-binding protein 1A Proteins

Many biological assays use antibodies to detect Myb-binding protein 1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Myb-binding protein 1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Myb-binding protein 1A antibodies...

We validate the specificity of these antibodies to Myb-binding protein 1A by testing them on tissues known to express MYBBP1A positively and negatively. Browse below to find the MYBBP1A antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MYBBP1A Infographic by Boster Bio

All MYBBP1A Products

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Product

Figures

Specificity

Applications

Price

Anti-MYBBP1A Monoclonal Antibody

5 Q&As

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M04187
100 μl

Anti-Myb-binding protein 1A MYBBP1A Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A04187
100ul

Anti-Myb-binding protein 1A MYBBP1A Antibody

Human

Flow Cytometry, IF, IHC, ICC, WB

$405
Cat # A04187-1
100ul

Anti-MYBBP1A Antibody

Human

$299
Cat # M04187-1
50 µl

MYBBP1A (NM_014520) Human Over-expression Lysate

Human

$628
Cat # LS010514
100 µg

MYBBP1A Overview

Facts about Myb-binding protein 1A.

MYBBP1A 3D structure. Source: alphafold

Myb-binding protein 1A (MYBBP1A)

May activate or repress transcription through connections with sequence specific DNA-binding proteins (By similarity). Repression could be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity).

Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity).

Gene Information

Human
Gene Name:	MYBBP1A
Uniprot:	Q9BQG0
Entrez:	10514

Family

Belongs to:

MYBBP1A family

Alternative Names

MYB binding protein (P160) 1a; myb-binding protein 1A; P160FLJ37886; p53-activated protein-2; PAP2

Molecular Weight

Mass (kDA):
148.855 kDA

Genomic Context


Human

Location:	17p13.2
Sequence:	17; NC_000017.11 (4538896..4555386, complement)

Subcellular Localizations

Cytoplasm. Nucleus. Nucleus, nucleolus. Shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1 (By similarity). Predominantly nucleolar.

Diseases

Neoplasms
Malignant Neoplasms
Mammary Neoplasms
Malignant Neoplasm Of Breast
Liver Carcinoma
Cell Transformation, Neoplastic
Neoplasm Metastasis
Sarcoma
Carcinoma
Myeloid Leukemia
Neoplasm Recurrence, Local
Diabetes Mellitus

Liver Neoplasms
Leukemia, Myelocytic, Acute
Leukemia
Sarcoma 180
Embryonal Carcinoma
Thymoma
Sudden Infant Death Syndrome

Pathways

Localization
Cell Cycle
Chromatin Remodeling
Cell Proliferation
Mitosis
Ribosome Biogenesis
Nuclear Export
Cytokinesis
Nuclear Import
Methylation
Cellular Localization
Cell Growth
Rrna Transcription

Transport
Atp-dependent Chromatin Remodeling
Gene Silencing
Electron Transport
Gluconeogenesis
Cell Cycle Arrest
Blastocyst Formation

PTMs

Acetylation
Methylation
Phosphorylation

Cleavage
Dephosphorylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MYBBP1A

References

PMID: 10644447 by Keough R., et al. Molecular cloning and chromosomal mapping of the human homologue of MYB binding protein (P160) 1A (MYBBP1A) to 17p13.3.

PMID: 16603771 by Cavellan E., et al. The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription.