MX2 Antibodies

AND MX2 ELISA kits, MX2 Proteins

Many biological assays use antibodies to detect MX2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MX2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MX2 antibodies...

We validate the specificity of these antibodies to MX2 by testing them on tissues known to express MX2 positively and negatively. Browse below to find the MX2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MX2 Infographic by Boster Bio

All MX2 Products

Product

Figures

Specificity

Applications

Price

Anti-MX2 Antibody

1 Q&As

Human

$360
Cat # A02330
100 µl

Anti-MX2 Antibody

Human, Mouse, Rat

$405
Cat # A02330-1
100ul

Human MX2 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTP20592
Starting from 20ug

MX2 (NM_002463) Human Over-expression Lysate

Human

$628
Cat # LS004600
100 µg

MX2 Overview

Facts about Interferon-induced GTP-binding protein Mx2.

MX2 3D structure. Source: alphafold

Interferon-induced GTP-binding protein Mx2 (MX2)

Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the following chromosomal integration of the proviral DNA.

Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle development.

Gene Information

Human
Gene Name:	MX2
Uniprot:	P20592
Entrez:	4600

Family

Belongs to:

TRAFAC class dynamin-like GTPase superfamily

Alternative Names

human interferon-regulated resistance GTP-binding protein MXB10Interferon-regulated resistance GTP-binding protein MxB; interferon-induced GTP-binding protein Mx2; MXB; myxovirus (influenza virus) resistance 2 (mouse); myxovirus (influenza) resistance 2, homolog of murine; Myxovirus resistance protein 2; p78-related protein; second interferon-induced protein p78

Molecular Weight

Mass (kDA):
82.089 kDA

Genomic Context


Human

Location:	21q22.3
Sequence:	21; NC_000021.9 (41361944..41409393)

Subcellular Localizations

Cytoplasm. Nucleus. Nucleus, nuclear pore complex. Localization to nuclear pores requires GTP-binding.

Diseases

Neoplasms
Leukemia
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Glioma
Influenza
Malignant Glioma
Vesicular Stomatitis
Stomatitis
Brain Neoplasms
Acute Promyelocytic Leukemia
Malignant Neoplasm Of Breast
Myeloid Leukemia

Mammary Neoplasms
Fish Diseases
Infective Disorder
Acute Lymphocytic Leukemia
Virus Diseases
Leukopenia
Leukemia, Myelocytic, Acute

Interacting Proteins

ATRIP
PIAS2

Pathways

Drug Resistance
Localization
Cell Death
Immune Response
Cell Growth
Cell Cycle
Translation
Innate Immune Response
Estrus
Cell Proliferation
Induction Of Apoptosis
Insemination
Transport

Cellular Respiration
Methylation
Cellular Localization
Pathogenesis
Viral Replication
Secretion
Cell Activation

PTMs

Cleavage
Reduction
Methylation

Demethylation
Glutathionylation
Acetylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MX2

References

PMID: 2481229 by Aebi M., et al. cDNA structures and regulation of two interferon-induced human Mx proteins.

PMID: 2154602 by Horisberger M.A., et al. Cloning and sequence analyses of cDNAs for interferon- and virus- induced human Mx proteins reveal that they contain putative guanine nucleotide-binding sites: functional study of the corresponding gene promoter.