Mucin-6 Antibodies

AND MUC6 ELISA kits, Mucin-6 Proteins

Many biological assays use antibodies to detect Mucin-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mucin-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mucin-6 antibodies...

We validate the specificity of these antibodies to Mucin-6 by testing them on tissues known to express MUC6 positively and negatively. Browse below to find the MUC6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MUC6 Infographic by Boster Bio

All MUC6 Products

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Product

Figures

Specificity

Applications

Price

Anti-MUC6 (Mucin 6 / Gastric Mucin) Monoclonal Antibody

2 Citations 6 Q&As

Human

IHC

$486
Cat # M02143
100ug/vial

Anti-Gastric Mucin/MUC6 Antibody Picoband®

1 Citations 1 Q&As

Human, Mouse

ELISA, WB

$370
Cat # A02143
100 μg/vial

Anti-Mucin-6 MUC6 Antibody

Human, Mouse, Rat

$405
Cat # A02143-1
100ul

MUC6 Overview

Facts about Mucin-6.

MUC6 3D structure. Source: alphafold

Mucin-6 (MUC6)

May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the existence of bacteria and noxious agents in the lumen. Plays an essential role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers.

May play a role in epithelial organogenesis. .

Gene Information

Human
Gene Name:	MUC6
Uniprot:	Q6W4X9
Entrez:	4588

Family

Belongs to:

No superfamily

Alternative Names

gastric mucin; Gastric mucin-6; MUC-6; mucin 6, gastric; mucin 6, oligomeric mucus/gel-forming; mucin-6

Molecular Weight

Mass (kDA):
257.051 kDA

Genomic Context


Human

Location:	11p15.5
Sequence:	11; NC_000011.10 (1012823..1036718, complement)

Tissue Specificity

Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct.

Subcellular Localizations

Secreted.

Diseases

Neoplasms
Carcinoma
Adenocarcinoma
Malignant Neoplasms
Stomach Neoplasms
Mucinous Adenocarcinoma
Malignant Neoplasm Of Stomach
Adenoma
Metaplasia
Malignant Paraganglionic Neoplasm
Neoplasm Metastasis
Carcinogenesis

Hyperplasia
Dysplasia
Cell Invasion
Pancreatic Neoplasm
Precancerous Conditions
Cell Transformation, Neoplastic
Helicobacter Infections

Pathways

Secretion
Glycosylation
Pathogenesis
Cell Differentiation
Localization
Mucus Secretion
Cell Adhesion
Cell Proliferation
Gallstone Formation
Dedifferentiation
Epithelial Cell Differentiation
Transdifferentiation
Transport

Immune Response
Cell Cycle
Epithelial Cell Proliferation
Methylation
Ovulation
Notch Signaling Pathway
Mismatch Repair

PTMs

Glycosylation
Deglycosylation
Methylation

Sulphation
Phosphorylation
Demethylation

Nitration

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MUC6

References

PMID: 15081123 by Rousseau K., et al. The complete genomic organization of the human MUC6 and MUC2 mucin genes.

PMID: 7680650 by Toribara N.W., et al. Human gastric mucin. Identification of a unique species by expression cloning.

2 Publications of Boster Mucin-6 Antibodies & ELISA Kits

PubMed ID: 10.1186/1746-1596-6-102, Mucins Differently Expressed in Various Ampullary Adenocarcinomas
PubMed ID: 22027009, Mucins Differently Expressed in Various Ampullary Adenocarcinomas

*More publications can be found for each product on its corresponding product page