Mucin-5B Antibodies

AND MUC5B ELISA kits, Mucin-5B Proteins

Many biological assays use antibodies to detect Mucin-5B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mucin-5B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mucin-5B antibodies...

We validate the specificity of these antibodies to Mucin-5B by testing them on tissues known to express MUC5B positively and negatively. Browse below to find the MUC5B antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: MROH1

MUC5B Infographic by Boster Bio

All MUC5B Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MUC5B Monoclonal Antibody

Human

Flow Cytometry, WB

$370
Cat # M00719
100 μl

Anti-Mucin-5B MUC5B Antibody

Human

IHC

$380
Cat # A00719
100ul

Anti-MUC5B Antibody

Human

ELISA, IHC

$370
Cat # A00719-2
100 μg/vial

MUC5B Overview

Facts about Mucin-5B.

Mucin-5B (MUC5B)

Gel-forming mucin that's thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. .

Gene Information

Human
Gene Name:	MUC5B
Uniprot:	Q9HC84
Entrez:	727897

Family

Belongs to:

No superfamily

Alternative Names

high molecular weight salivary mucin MG1; mucin 5, subtype B, tracheobronchial; mucin 5B, oligomeric mucus/gel-forming; sublingual gland mucin; tracheobronchial

Molecular Weight

Mass (kDA):
596.34 kDA

Genomic Context


Human

Location:	11p15.5
Sequence:	11; NC_000011.10 (1223066..1262172)

Tissue Specificity

Expressed on surface airway epithelia. Expressed mainly in mucous cells of submucosal glands of airway tissues. Highly expressed in the sublingual gland. Also found in submaxillary glands, endocervix, gall bladder, and pancreas.

Subcellular Localizations

Secreted.

Diseases

Mucinous Adenocarcinoma
Malignant Neoplasms
Neoplasms
Inflammation
Fibrosis
Carcinoma
Adenocarcinoma
Asthma
Cystic Fibrosis
Lung Diseases
Salivary Gland Diseases
Metaplasia

Hyperplasia
Chronic Obstructive Airway Disease
Lung Diseases, Obstructive
Otitis Media
Ear Inflammation
Tissue Adhesions
Sinusitis

Pathways

Secretion
Pathogenesis
Glycosylation
Localization
Cell Differentiation
Mucus Secretion
Cell Proliferation
Gallstone Formation
Transport
Proteolysis
Immune Response
Epithelial Cell Differentiation
Sulfation

Ovulation
Inflammatory Response
Translation
Epithelial Cell Proliferation
Cell Adhesion
Cell Migration
Lung Development

PTMs

Glycosylation
Phosphorylation
Cleavage
Deglycosylation
Methylation

Sulphation
Oxidation
Demethylation
Carbamylation
C-mannosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MUC5B

References

PMID: 11713095 by Chen Y., et al. Characterization of human mucin 5B gene expression in airway epithelium and the genomic clone of the amino-terminal and 5'-flanking region.

PMID: 9790959 by Offner G.D., et al. The amino-terminal sequence of MUC5B contains conserved multifunctional D domains: implications for tissue-specific mucin functions.