MTMR1 Antibodies

AND MTMR1 ELISA kits, MTMR1 Proteins

Many biological assays use antibodies to detect MTMR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTMR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTMR1 antibodies...

We validate the specificity of these antibodies to MTMR1 by testing them on tissues known to express MTMR1 positively and negatively. Browse below to find the MTMR1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MTMR1 Infographic by Boster Bio

All MTMR1 Products

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Price

MTMR1 (NM_003828) Human Recombinant Protein

$813
Cat # PROTQ13613
20 µg

MTMR1 (NM_003828) Human Over-expression Lysate

Human

$960
Cat # LS008776
100 µg

MTMR1 Overview

Facts about Myotubularin-related protein 1.

MTMR1 3D structure. Source: alphafold

Myotubularin-related protein 1 (MTMR1)

Lipid phosphatase that has high specificity for phosphatidylinositol 3-phosphate and has no action with phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)- bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate (PubMed:11733541, PubMed:27018598). Activity with phosphatidylinositol (3,5)-bisphosphate is controversial; it has been proven by PubMed:27018598, while PubMed:11733541 find no activity with this substrate.

Gene Information

Human
Gene Name:	MTMR1
Uniprot:	Q13613
Entrez:	8776

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

EC 3.1.3; EC 3.1.3.-; EC 3.1.3.48; myotubularin related protein 1; myotubularin-related protein 1

Molecular Weight

Mass (kDA):
74.678 kDA

Genomic Context


Human

Location:	Xq28
Sequence:	X; NC_000023.11 (150692962..150765108)

Subcellular Localizations

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm.

Diseases

Myopathy
Congenital Structural Myopathy
Myotonic Dystrophy
Dystrophy
Dystrophia Myotonica 2
Charcot-marie-tooth Disease
Weakness
Neurodegenerative Disorders
Neuromuscular Diseases
Malignant Neoplasm Of Lung
Carcinoma
Malignant Neoplasms

Congenital Myotonic Dystrophy
Generalized Muscle Weakness
Hereditary Diseases
Lung Neoplasms
Tissue Adhesions
Muscle Hypotonia
Sex Chromosome Aberrations

Pathways

Pathogenesis
Cell Adhesion
Mrna Splicing
Somitogenesis
Rna Processing
Localization

PTMs

Dephosphorylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTMR1

References

PMID: 9828128 by Kioschis P., et al. Genomic organization of a 225-kb region in Xq28 containing the gene for X-linked myotubular myopathy (MTM1) and a related gene (MTMR1).

PMID: 9736772 by Laporte J., et al. Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.