MTERF3 Antibodies

AND MTERF3 ELISA kits, MTERF3 Proteins

Many biological assays use antibodies to detect MTERF3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MTERF3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MTERF3 antibodies...

We validate the specificity of these antibodies to MTERF3 by testing them on tissues known to express MTERF3 positively and negatively. Browse below to find the MTERF3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MTERF3 Infographic by Boster Bio

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MTERF3 Overview

Facts about Transcription termination factor 3, mitochondrial.

MTERF3 3D structure. Source: alphafold

Transcription termination factor 3, mitochondrial (MTERF3)

Binds promoter DNA and regulates initiation of transcription (PubMed:17662942). Required for normal mitochondrial transcription and translation, and for regular assembly of mitochondrial respiratory complexes.

Required for normal mitochondrial function (By similarity). Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit (By similarity).

Gene Information

Human
Gene Name:	MTERF3
Uniprot:	Q96E29
Entrez:	51001

Family

Belongs to:

mTERF family

Alternative Names

CGI-12; FLJ10939; Mitochondrial transcription termination factor 3; MTERF domain containing 1; mTERF domain-containing protein 1, mitochondrial; mTERF3

Molecular Weight

Mass (kDA):
47.971 kDA

Genomic Context


Human

Location:	8q22.1
Sequence:	8; NC_000008.11 (96239398..96261613, complement)

Tissue Specificity

Highly expressed in heart, liver, kidney and testis. Detected at lower levels in brain, spleen and lung.

Subcellular Localizations

Mitochondrion.

Interacting Proteins

AGTRAP
ARL6IP1
CMTM5
FUNDC1

Pathways

Mitochondrial Dna Replication
Dna Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MTERF3

References

PMID: 17662942 by Park C.B., et al. MTERF3 is a negative regulator of mammalian mtDNA transcription.

PMID: 20430012 by Spaahr H., et al. Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain.